RRM1

Description		ribonucleotide reductase catalytic subunit M1
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GO Annotations	Cellular Component	Nuclear Envelope Cytosol Ribonucleoside-diphosphate Reductase Complex Cell Projection Neuronal Cell Body
	Molecular Function	Ribonucleoside-diphosphate Reductase Activity, Thioredoxin Disulfide As Acceptor Protein Binding ATP Binding Identical Protein Binding Ribonucleoside-diphosphate Reductase Activity Disordered Domain Specific Binding
	Biological Process	Mitotic Cell Cycle Pyrimidine Nucleobase Metabolic Process DNA Replication Male Gonad Development Deoxyribonucleotide Biosynthetic Process Response To Ionizing Radiation Nucleobase-containing Small Molecule Interconversion Cell Proliferation In Forebrain Protein Heterotetramerization Oxidation-reduction Process Retina Development In Camera-type Eye
Pathways		Interconversion of nucleotide di- and triphosphates
Drugs		Cladribine Gemcitabine Clofarabine Hydroxyurea Fludarabine Imexon gallium maltolate
Diseases
GWAS		Mean corpuscular hemoglobin ( 29403010) Red cell distribution width ( 27863252 28957414)
Interacting Genes		8 interacting genes: BMI1 LRIF1 NUP98 PPP1CC RNF2 RRM2 RRM2B YWHAG
Entrez ID		6240
HPRD ID		01588
Ensembl ID		ENSG00000167325
Uniprot IDs		B4DXD1 B4E0I8 E9PL69 P23921
PDB IDs		2WGH 3HNC 3HND 3HNE 3HNF 4X3V 5D1Y 5TUS 6AUI
Enriched GO Terms of Interacting Partners?
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