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RHEB

Description Ras homolog, mTORC1 binding
Image
GO Annotations Cellular Component
  • Golgi Membrane
  • Spliceosomal Complex
  • Lysosomal Membrane
  • Endoplasmic Reticulum Membrane
  • Cytosol
  • Plasma Membrane
  • Postsynaptic Density
  • Membrane
  • Extracellular Exosome
Molecular Function
  • Magnesium Ion Binding
  • GTPase Activity
  • Protein Binding
  • GTP Binding
  • GDP Binding
  • Protein Kinase Binding
Biological Process
  • Cell Cycle Arrest
  • Signal Transduction
  • Small GTPase Mediated Signal Transduction
  • Regulation Of Macroautophagy
  • Positive Regulation Of TOR Signaling
  • Positive Regulation Of Oligodendrocyte Differentiation
  • Negative Regulation Of Cold-induced Thermogenesis
  • Regulation Of Type B Pancreatic Cell Development
Pathways
  • Macroautophagy
  • mTOR signalling
  • mTORC1-mediated signalling
  • Energy dependent regulation of mTOR by LKB1-AMPK
  • TP53 Regulates Metabolic Genes
  • Regulation of PTEN gene transcription
  • Amino acids regulate mTORC1
Drugs
  • Guanosine-5'-Triphosphate
  • Guanosine-5'-Diphosphate
Diseases
GWAS
  • Carboplatin disposition in epthelial ovarian cancer ( 29367611)
  • Metabolite levels ( 23823483)
Interacting Genes 26 interacting genes: A2M APOE ARIH2 ATM ATR BNIP3 BNIP3L BRAF CREB3 ECSIT FKBP8 HTT MTOR NCAM1 PDE6D PLD1 PSEN1 PSEN2 RABAC1 RAF1 RNF152 RPS6KB1 RPTOR TSC1 TSC2 USP4
Entrez ID 6009
HPRD ID 03188
Ensembl ID ENSG00000106615
Uniprot IDs A0A090N900 Q15382
PDB IDs 1XTQ 1XTR 1XTS 3SEA 3T5G 5YXH 6BCU 6BSX 6BT0
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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