POLE3

Description		DNA polymerase epsilon 3, accessory subunit
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Ada2/Gcn5/Ada3 Transcription Activator Complex Epsilon DNA Polymerase Complex CHRAC
	Molecular Function	DNA-directed DNA Polymerase Activity Protein Binding Chromatin DNA Binding Protein Heterodimerization Activity
	Biological Process	G1/S Transition Of Mitotic Cell Cycle DNA Replication DNA Replication Initiation Leading Strand Elongation Cellular Response To DNA Damage Stimulus Telomere Maintenance Via Semi-conservative Replication Nucleosome Mobilization Histone H3 Acetylation Heterochromatin Assembly Involved In Chromatin Silencing DNA Biosynthetic Process
Pathways		Recognition of DNA damage by PCNA-containing replication complex PCNA-Dependent Long Patch Base Excision Repair Termination of translesion DNA synthesis HDR through Homologous Recombination (HRR) Gap-filling DNA repair synthesis and ligation in GG-NER Dual Incision in GG-NER Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER DNA replication initiation Activation of the pre-replicative complex
Drugs		Cladribine
Diseases
GWAS
Interacting Genes		7 interacting genes: APP BAZ1A CHRAC1 DR1 DRAP1 POLE4 SMARCA5
Entrez ID		54107
HPRD ID		06274
Ensembl ID		ENSG00000148229
Uniprot IDs		A0A024R829 Q9NRF9
PDB IDs
Enriched GO Terms of Interacting Partners?
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