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PGGT1B

Description protein geranylgeranyltransferase type I subunit beta
Image No pdb structure
GO Annotations Cellular Component
  • CAAX-protein Geranylgeranyltransferase Complex
Molecular Function
  • Protein Geranylgeranyltransferase Activity
  • CAAX-protein Geranylgeranyltransferase Activity
  • Drug Binding
  • Zinc Ion Binding
  • Isoprenoid Binding
  • Peptide Binding
Biological Process
  • Positive Regulation Of Cell Proliferation
  • Protein Prenylation
  • Protein Geranylgeranylation
  • Response To Cytokine
  • Positive Regulation Of Cell Cycle
  • Negative Regulation Of Nitric-oxide Synthase Biosynthetic Process
Pathways
Drugs
  • 4-[(5-{[4-(3-CHLOROPHENYL)-3-OXOPIPERAZIN-1-YL]METHYL}-1H-IMIDAZOL-1-YL)METHYL]BENZONITRILE
  • Geranylgeranyl diphosphate
  • 2-[METHYL-(5-GERANYL-4-METHYL-PENT-3-ENYL)-AMINO]-ETHYL-DIPHOSPHATE
Diseases
GWAS
  • Longevity ( 30294719)
Interacting Genes 5 interacting genes: CDC42 GNG2 KRAS RHOB RRAS2
Entrez ID 5229
HPRD ID 03612
Ensembl ID ENSG00000164219
Uniprot IDs P53609
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025

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