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HIC1

Description HIC ZBTB transcriptional repressor 1
Image No pdb structure
GO Annotations Cellular Component
  • Chromatin
  • Nucleus
  • Nucleoplasm
Molecular Function
  • DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
  • DNA-binding Transcription Factor Activity
  • Protein Binding
  • Histone Deacetylase Binding
  • Sequence-specific DNA Binding
  • Metal Ion Binding
Biological Process
  • Negative Regulation Of Transcription By RNA Polymerase II
  • Regulation Of Transcription, DNA-templated
  • Cellular Response To DNA Damage Stimulus
  • Multicellular Organism Development
  • Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
  • Wnt Signaling Pathway
  • Negative Regulation Of Wnt Signaling Pathway
  • Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator
Pathways
  • SUMOylation of transcription factors
Drugs
Diseases
GWAS
  • Plasma anti-thyroglobulin and anti-thyroid peroxidase levels (bivariate analysis) ( 29678681)
  • Platelet count ( 27863252)
  • Plateletcrit ( 27863252)
Interacting Genes 12 interacting genes: ARID1A CRBN CTBP1 CTBP2 HDAC1 HIC2 MECOM PIAS1 SENP3 SIRT1 TCF7L2 UBE2I
Entrez ID 3090
HPRD ID 04826
Ensembl ID ENSG00000177374
Uniprot IDs A0PJI1 Q14526
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025

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