GRIN2C

Description		glutamate ionotropic receptor NMDA type subunit 2C
Image		No pdb structure
GO Annotations	Cellular Component	Cell Plasma Membrane Integral Component Of Plasma Membrane NMDA Selective Glutamate Receptor Complex Cell Junction Postsynaptic Membrane Postsynaptic Density Membrane Glutamatergic Synapse
	Molecular Function	NMDA Glutamate Receptor Activity Protein Binding Glutamate Receptor Activity Ligand-gated Ion Channel Activity Glutamate-gated Calcium Ion Channel Activity Signaling Receptor Activity Transmitter-gated Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential
	Biological Process	Glutamate Receptor Signaling Pathway Brain Development Response To Wounding Calcium-mediated Signaling Directional Locomotion Ionotropic Glutamate Receptor Signaling Pathway Synaptic Transmission, Glutamatergic Negative Regulation Of Protein Catabolic Process Regulation Of Synaptic Plasticity Modulation Of Chemical Synaptic Transmission Neuromuscular Process Controlling Balance Excitatory Postsynaptic Potential Long-term Synaptic Potentiation Calcium Ion Transmembrane Import Into Cytosol Excitatory Chemical Synaptic Transmission Protein Localization To Postsynaptic Membrane
Pathways		Unblocking of NMDA receptors, glutamate binding and activation Unblocking of NMDA receptors, glutamate binding and activation Neurexins and neuroligins Synaptic adhesion-like molecules Assembly and cell surface presentation of NMDA receptors Assembly and cell surface presentation of NMDA receptors Negative regulation of NMDA receptor-mediated neuronal transmission Long-term potentiation
Drugs		Glutamic Acid Glycine Atomoxetine Pentobarbital Secobarbital Pethidine Acamprosate Gabapentin Phenobarbital Tenocyclidine Prasterone Milnacipran Ketobemidone Gavestinel Magnesium acetate tetrahydrate Magnesium carbonate Fluciclovine (18F)
Diseases
GWAS		Congenital heart disease (maternal effect) ( 28468790)
Interacting Genes		6 interacting genes: DLG3 DLG4 DLGAP1 ERBIN IL16 PATJ
Entrez ID		2905
HPRD ID		00699
Ensembl ID		ENSG00000161509
Uniprot IDs		H0Y2V8 O15398 Q14957 Q8IW23
PDB IDs
Enriched GO Terms of Interacting Partners?
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