B4GALT7

Description		beta-1,4-galactosyltransferase 7
Image
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Integral Component Of Membrane Golgi Cisterna Membrane
	Molecular Function	Beta-N-acetylglucosaminylglycopeptide Beta-1,4-galactosyltransferase Activity Protein Binding Galactosyltransferase Activity Manganese Ion Binding Xylosylprotein 4-beta-galactosyltransferase Activity
	Biological Process	Carbohydrate Metabolic Process Glycosaminoglycan Biosynthetic Process Proteoglycan Metabolic Process Cellular Protein Modification Process Protein N-linked Glycosylation Glycosaminoglycan Metabolic Process Negative Regulation Of Fibroblast Proliferation Supramolecular Fiber Organization
Pathways		A tetrasaccharide linker sequence is required for GAG synthesis Defective B4GALT7 causes EDS, progeroid type
Drugs
Diseases		Ehlers-Danlos syndrome (EDS), including: EDS classical type (EDS1/2); EDS hypermobility type (EDS3); EDS vascular type (EDS4); EDS kyphoscoliosis type (EDS6); EDS arthrochalasia type (EDS7A/7B); EDS dermatospraxis type (EDS7C); EDS autosomal recessive cardiac valvular form (EDSCV); EDS musculocontractural type (EDSMC); EDS progeroid form (EDSP); Tenascin-X deficiency (TNXD); Brittle cornea syndrome (EDS6B); EDS-like spondylocheiro dysplasia (SCD-EDS) Ehlers-Danlos syndrome, progeroid form
GWAS		Blood protein levels ( 30072576) Methadone dose in opioid dependence ( 28115739) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		3 interacting genes: KRTAP10-3 KRTAP10-7 RABGGTB
Entrez ID		11285
HPRD ID		05060
Ensembl ID		ENSG00000027847
Uniprot IDs		B3KMT1 Q9UBV7
PDB IDs		4IRP 4IRQ
Enriched GO Terms of Interacting Partners?
Tagcloud ?