CDX2

Description		caudal type homeobox 2
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GO Annotations	Cellular Component	Nuclear Chromatin Condensed Nuclear Chromosome Nucleus Nucleoplasm Transcriptional Repressor Complex
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Transcription Corepressor Activity Methyl-CpG Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Blood Vessel Development Trophectodermal Cell Differentiation Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Positive Regulation Of Cell Proliferation Endosome To Lysosome Transport Embryo Development Animal Organ Morphogenesis Anterior/posterior Axis Specification Regulation Of Somitogenesis Cell Differentiation Somatic Stem Cell Population Maintenance Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Positive Regulation Of Cell Differentiation Positive Regulation Of Transcription, DNA-templated Intestinal Epithelial Cell Differentiation Labyrinthine Layer Development
Pathways		Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)
Drugs
Diseases
GWAS		Body mass index ( 26426971) Monocyte count ( 27863252) Pancreatic cancer ( 25086665)
Interacting Genes		14 interacting genes: ACAT2 CDK2 CREBBP DNMT3L EP300 GSK3B HNF1A MAPK1 MAPK14 PAX6 SMARCA4 SMARCB1 SMARCD1 UBB
Entrez ID		1045
HPRD ID		02622
Ensembl ID		ENSG00000165556
Uniprot IDs		Q99626
PDB IDs		5LTY 6ES2 6ES3
Enriched GO Terms of Interacting Partners?
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