| Novel |
AGO2
|
argonaute RISC catalytic component 2 |
- Pre-NOTCH Transcription and Translation
- MicroRNA (miRNA) biogenesis
- Ca2+ pathway
- Small interfering RNA (siRNA) biogenesis
- Post-transcriptional silencing by small RNAs
- Transcriptional regulation by small RNAs
- TP53 Regulates Metabolic Genes
- MAPK6/MAPK4 signaling
- Regulation of RUNX1 Expression and Activity
- Regulation of PTEN mRNA translation
- Competing endogenous RNAs (ceRNAs) regulate PTEN translation
- Transcriptional Regulation by MECP2
- Transcriptional Regulation by MECP2
- Estrogen-dependent gene expression
- Regulation of MECP2 expression and activity
- NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
- Nuclear events stimulated by ALK signaling in cancer
- Regulation of CDH11 mRNA translation by microRNAs
- Regulation of CDH11 mRNA translation by microRNAs
- Regulation of CDH1 mRNA translation by microRNAs
- Regulation of NPAS4 mRNA translation
- M-decay: degradation of maternal mRNAs by maternally stored factors
- Regulation of MITF-M-dependent genes involved in apoptosis
- TGFBR3 expression
- Regulation of PD-L1(CD274) translation
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|
|
| Novel |
CHTOP
|
chromatin target of PRMT1 |
- Transport of Mature mRNA derived from an Intron-Containing Transcript
- mRNA 3'-end processing
- RNA Polymerase II Transcription Termination
|
|
|
| Novel |
HAX1
|
HCLS1 associated protein X-1 |
|
|
- Neutropenic disorders, including the following three diseases: Kostmann syndrome; Cyclic neutropenia; X-linked neutropenia/myelodysplasia
|
| Novel |
KCNN3
|
potassium calcium-activated channel subfamily N member 3 |
- Ca2+ activated K+ channels
|
- Procaine
- Ritodrine
- Nitrendipine
- Miconazole
- Colforsin
- Dequalinium
- Trimebutine
- Rimtuzalcap
|
|
| Novel |
POGZ
|
pogo transposable element derived with ZNF domain |
|
|
|
| Novel |
SCIN
|
scinderin |
|
|
|
| Novel |
SLC27A3
|
solute carrier family 27 member 3 |
- Synthesis of very long-chain fatty acyl-CoAs
|
|
|
| Novel |
SMCP
|
sperm mitochondria associated cysteine rich protein |
|
|
|
| Novel |
TCHH
|
trichohyalin |
- Formation of the cornified envelope
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|
|
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ATXN1
|
ataxin 1 |
|
|
- Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
|
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FXR1
|
FMR1 autosomal homolog 1 |
- Signaling by BRAF and RAF1 fusions
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|
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G3BP1
|
G3BP stress granule assembly factor 1 |
- SARS-CoV-2 activates/modulates innate and adaptive immune responses
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|
|
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ITCH
|
itchy E3 ubiquitin protein ligase |
- Downregulation of ERBB4 signaling
- NOD1/2 Signaling Pathway
- Activated NOTCH1 Transmits Signal to the Nucleus
- Activated NOTCH1 Transmits Signal to the Nucleus
- Degradation of GLI1 by the proteasome
- Hedgehog 'on' state
- Regulation of necroptotic cell death
- RUNX1 regulates transcription of genes involved in differentiation of HSCs
- Negative regulators of DDX58/IFIH1 signaling
- SARS-CoV-1 activates/modulates innate immune responses
- Antigen processing: Ubiquitination & Proteasome degradation
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|
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LINC00624
|
long intergenic non-protein coding RNA 624 |
|
|
|
|
MTNR1A
|
melatonin receptor 1A |
- Class A/1 (Rhodopsin-like receptors)
- G alpha (i) signalling events
|
- Ramelteon
- Melatonin
- Resveratrol
- Agomelatine
- Tasimelteon
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|
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MTNR1B
|
melatonin receptor 1B |
- Class A/1 (Rhodopsin-like receptors)
- G alpha (i) signalling events
|
- Ramelteon
- Melatonin
- Resveratrol
- Agomelatine
- Tasimelteon
- Tepotinib
|
- Type II diabetes mellitus
|
|
NEDD4
|
NEDD4 E3 ubiquitin protein ligase |
- ISG15 antiviral mechanism
- Downregulation of ERBB4 signaling
- Regulation of PTEN localization
- Regulation of PTEN stability and activity
- Antigen processing: Ubiquitination & Proteasome degradation
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|
|
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PLXNA2
|
plexin A2 |
- Sema3A PAK dependent Axon repulsion
- SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
- SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
- CRMPs in Sema3A signaling
- CRMPs in Sema3A signaling
- Other semaphorin interactions
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PRRC2A
|
proline rich coiled-coil 2A |
|
|
|
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SUMO2
|
small ubiquitin like modifier 2 |
- Vitamin D (calciferol) metabolism
- SUMO is conjugated to E1 (UBA2:SAE1)
- SUMO is transferred from E1 to E2 (UBE2I, UBC9)
- SUMO is proteolytically processed
- SUMOylation of DNA damage response and repair proteins
- SUMOylation of transcription factors
- SUMOylation of transcription cofactors
- SUMOylation of SUMOylation proteins
- SUMOylation of intracellular receptors
- SUMOylation of intracellular receptors
- SUMOylation of chromatin organization proteins
- SUMOylation of RNA binding proteins
- SUMOylation of DNA replication proteins
- Processing of DNA double-strand break ends
- Formation of Incision Complex in GG-NER
- Regulation of endogenous retroelements by KRAB-ZFP proteins
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