Search Results for: TNFAIP3

62 interactions involving TNFAIP3 - TNF alpha induced protein 3 found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Symbol Description Pathways Hide Drugs Hide Diseases Hide
Novel EAPP E2F associated phosphoprotein
ANKRD13D ankyrin repeat domain 13D
ARRDC3 arrestin domain containing 3
ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
  • Pre-NOTCH Processing in Golgi
  • Reduction of cytosolic Ca++ levels
  • Ion homeostasis
  • Ion transport by P-type ATPases
  • Ritodrine
  • Desflurane
  • Sevoflurane
  • Istaroxime
  • Acrokeratosis verruciformis
  • Darier disease; Dyskeratosis follicularis
CALCOCO2 calcium binding and coiled-coil domain 2
CCDC50 coiled-coil domain containing 50
CCDC90B coiled-coil domain containing 90B
CHUK component of inhibitor of nuclear factor kappa B kinase complex
  • Activation of NF-kappaB in B cells
  • Activation of NF-kappaB in B cells
  • ER-Phagosome pathway
  • NOD1/2 Signaling Pathway
  • TICAM1, RIP1-mediated IKK complex recruitment
  • RIP-mediated NFkB activation via ZBP1
  • AKT phosphorylates targets in the cytosol
  • Downstream TCR signaling
  • FCERI mediated NF-kB activation
  • TAK1-dependent IKK and NF-kappa-B activation
  • Regulation of TNFR1 signaling
  • TNFR1-induced NF-kappa-B signaling pathway
  • IKBKB deficiency causes SCID
  • IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)
  • IkBA variant leads to EDA-ID
  • Dectin-1 mediated noncanonical NF-kB signaling
  • CLEC7A (Dectin-1) signaling
  • Constitutive Signaling by AKT1 E17K in Cancer
  • NIK-->noncanonical NF-kB signaling
  • MAP3K8 (TPL2)-dependent MAPK1/3 activation
  • Interleukin-1 signaling
  • TRAF6 mediated NF-kB activation
  • NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
  • IRAK1 recruits IKK complex
  • IKK complex recruitment mediated by RIP1
  • SARS-CoV-2 activates/modulates innate and adaptive immune responses
  • IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation
  • Regulation of NF-kappa B signaling
  • PKR-mediated signaling
  • SLC15A4:TASL-dependent IRF5 activation
  • Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells
  • Modulation of host responses by IFN-stimulated genes
  • Aminosalicylic acid
  • Mesalazine
  • Acetylcysteine
  • Cocoon syndrome
CLEC4G C-type lectin domain family 4 member G
  • Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
COL1A1 collagen type I alpha 1 chain
  • GPVI-mediated activation cascade
  • Collagen degradation
  • Collagen degradation
  • Fibronectin matrix formation
  • Collagen biosynthesis and modifying enzymes
  • Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
  • Assembly of collagen fibrils and other multimeric structures
  • Cell surface interactions at the vascular wall
  • Integrin cell surface interactions
  • Integrin cell surface interactions
  • Anchoring fibril formation
  • Crosslinking of collagen fibrils
  • Syndecan interactions
  • Non-integrin membrane-ECM interactions
  • ECM proteoglycans
  • ECM proteoglycans
  • Scavenging by Class A Receptors
  • GP1b-IX-V activation signalling
  • Platelet Adhesion to exposed collagen
  • Platelet Adhesion to exposed collagen
  • Platelet Aggregation (Plug Formation)
  • MET activates PTK2 signaling
  • RUNX2 regulates osteoblast differentiation
  • Collagen chain trimerization
  • Enhanced cleavage of VWF variant by ADAMTS13
  • Enhanced binding of GP1BA variant to VWF multimer:collagen
  • Defective VWF cleavage by ADAMTS13 variant
  • Defective VWF binding to collagen type I
  • Defective binding of VWF variant to GPIb:IX:V
  • Developmental Lineage of Pancreatic Ductal Cells
  • Collagenase clostridium histolyticum
  • Halofuginone
  • Clove oil
  • Vonicog alfa
  • Von Willebrand factor human
  • Osteogenesis imperfecta
  • Ehlers-Danlos syndrome (EDS), including: EDS classical type (EDS1/2); EDS hypermobility type (EDS3); EDS vascular type (EDS4); EDS kyphoscoliosis type (EDS6); EDS arthrochalasia type (EDS7A/7B); EDS dermatospraxis type (EDS7C); EDS autosomal recessive cardiac valvular form (EDSCV); EDS musculocontractural type (EDSMC); EDS progeroid form (EDSP); Tenascin-X deficiency (TNXD); Brittle cornea syndrome (EDS6B); EDS-like spondylocheiro dysplasia (SCD-EDS)
  • Infantile cortical hyperostosis; Caffey disease
DRC4 dynein regulatory complex subunit 4
  • Activation of SMO
FABP4 fatty acid binding protein 4
  • Triglyceride catabolism
  • Triglyceride catabolism
  • Transcriptional regulation of white adipocyte differentiation
  • Transcriptional regulation of white adipocyte differentiation
  • MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
GIT2 GIT ArfGAP 2
  • CDC42 GTPase cycle
  • RAC1 GTPase cycle
  • RAC2 GTPase cycle
  • RHOQ GTPase cycle
  • RHOJ GTPase cycle
  • RHOU GTPase cycle
  • RAC3 GTPase cycle
  • RHOV GTPase cycle
GNAI2 G protein subunit alpha i2
  • Adenylate cyclase inhibitory pathway
  • Adenylate cyclase inhibitory pathway
  • ADP signalling through P2Y purinoceptor 12
  • Adrenaline,noradrenaline inhibits insulin secretion
  • Adrenaline,noradrenaline inhibits insulin secretion
  • G alpha (s) signalling events
  • G alpha (i) signalling events
  • G alpha (i) signalling events
  • G alpha (z) signalling events
  • Regulation of insulin secretion
  • Extra-nuclear estrogen signaling
  • GPER1 signaling
  • ADORA2B mediated anti-inflammatory cytokines production
  • Adrenal carcinoma
IKBKB inhibitor of nuclear factor kappa B kinase subunit beta
  • Activation of NF-kappaB in B cells
  • Activation of NF-kappaB in B cells
  • ER-Phagosome pathway
  • NOD1/2 Signaling Pathway
  • TICAM1, RIP1-mediated IKK complex recruitment
  • RIP-mediated NFkB activation via ZBP1
  • Downstream TCR signaling
  • p75NTR recruits signalling complexes
  • NF-kB is activated and signals survival
  • FCERI mediated NF-kB activation
  • TAK1-dependent IKK and NF-kappa-B activation
  • Regulation of TNFR1 signaling
  • TNFR1-induced NF-kappa-B signaling pathway
  • IKBKB deficiency causes SCID
  • IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)
  • IkBA variant leads to EDA-ID
  • CLEC7A (Dectin-1) signaling
  • MAP3K8 (TPL2)-dependent MAPK1/3 activation
  • Interleukin-1 signaling
  • TRAF6 mediated NF-kB activation
  • NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
  • IRAK1 recruits IKK complex
  • IKK complex recruitment mediated by RIP1
  • SARS-CoV-2 activates/modulates innate and adaptive immune responses
  • IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation
  • Regulation of NF-kappa B signaling
  • PKR-mediated signaling
  • SLC15A4:TASL-dependent IRF5 activation
  • Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells
  • Modulation of host responses by IFN-stimulated genes
  • Mesalazine
  • Acetylsalicylic acid
  • Auranofin
  • Arsenic trioxide
  • MLN0415
  • Acetylcysteine
  • Ertiprotafib
  • Fostamatinib
IKBKG inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
  • Activation of NF-kappaB in B cells
  • Activation of NF-kappaB in B cells
  • ER-Phagosome pathway
  • NOD1/2 Signaling Pathway
  • TICAM1, RIP1-mediated IKK complex recruitment
  • RIP-mediated NFkB activation via ZBP1
  • Downstream TCR signaling
  • FCERI mediated NF-kB activation
  • TAK1-dependent IKK and NF-kappa-B activation
  • activated TAK1 mediates p38 MAPK activation
  • JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
  • SUMOylation of immune response proteins
  • Regulation of TNFR1 signaling
  • TNFR1-induced NF-kappa-B signaling pathway
  • IKBKB deficiency causes SCID
  • IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)
  • IkBA variant leads to EDA-ID
  • CLEC7A (Dectin-1) signaling
  • MAP3K8 (TPL2)-dependent MAPK1/3 activation
  • Ub-specific processing proteases
  • Ovarian tumor domain proteases
  • Interleukin-1 signaling
  • TRAF6 mediated NF-kB activation
  • NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
  • IRAK1 recruits IKK complex
  • IKK complex recruitment mediated by RIP1
  • SARS-CoV-2 activates/modulates innate and adaptive immune responses
  • IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation
  • Regulation of NF-kappa B signaling
  • PKR-mediated signaling
  • SLC15A4:TASL-dependent IRF5 activation
  • Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells
  • Modulation of host responses by IFN-stimulated genes
  • AGRO100
  • Tarenflurbil
  • Incontinentia pigmenti
  • Ectodermal dysplasia associated immunodeficiency (EDA-ID), including the following two diseases: NF-kappa-B essential modulator (NEMO) defect; Inhibitor of kappa-B (I-kappa-B) defect
  • Osteoporosis, lymphedema, anhydrotic ectodermal dysplasia with immunodeficiency (OLEDAID); Ectodermal dysplasia, anhidrotic, with immunodeficiency, osteopetrosis, and lymphedema
LAPTM5 lysosomal protein transmembrane 5
LNX1 ligand of numb-protein X 1
  • Antigen processing: Ubiquitination & Proteasome degradation
MAP3K5 mitogen-activated protein kinase kinase kinase 5
  • Oxidative Stress Induced Senescence
  • Oxidative Stress Induced Senescence
OCLN occludin
  • Apoptotic cleavage of cell adhesion proteins
  • RUNX1 regulates expression of components of tight junctions
  • Band-like calcification with simplified gyration and polymicrogyria (BLC-PMG); Pseudo-TORCH syndrome

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