| Novel |
DMPK
|
DM1 protein kinase |
|
|
|
| Novel |
GMEB2
|
glucocorticoid modulatory element binding protein 2 |
|
|
|
| Novel |
NECTIN2
|
nectin cell adhesion molecule 2 |
- Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
- Adherens junctions interactions
- Nectin/Necl trans heterodimerization
|
|
|
| Novel |
PLAT
|
plasminogen activator, tissue type |
- Signaling by PDGF
- Dissolution of Fibrin Clot
|
- Aminocaproic acid
- Iloprost
- Human C1-esterase inhibitor
- 5-(DIMETHYLAMINO)-2-NAPHTHALENESULFONIC ACID
- Dexibuprofen
- Conestat alfa
|
|
| Novel |
PSG11
|
pregnancy specific beta-1-glycoprotein 11 |
- Cell surface interactions at the vascular wall
|
|
|
| Novel |
PSG9
|
pregnancy specific beta-1-glycoprotein 9 |
- Cell surface interactions at the vascular wall
|
|
|
| Novel |
PSMD8
|
proteasome 26S subunit, non-ATPase 8 |
- Activation of NF-kappaB in B cells
- Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
- ER-Phagosome pathway
- Cross-presentation of soluble exogenous antigens (endosomes)
- Autodegradation of Cdh1 by Cdh1:APC/C
- SCF-beta-TrCP mediated degradation of Emi1
- APC/C:Cdc20 mediated degradation of Securin
- APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
- Cdc20:Phospho-APC/C mediated degradation of Cyclin A
- Vpu mediated degradation of CD4
- Vif-mediated degradation of APOBEC3G
- SCF(Skp2)-mediated degradation of p27/p21
- Degradation of beta-catenin by the destruction complex
- Downstream TCR signaling
- Regulation of activated PAK-2p34 by proteasome mediated degradation
- Separation of Sister Chromatids
- FCERI mediated NF-kB activation
- Autodegradation of the E3 ubiquitin ligase COP1
- Regulation of ornithine decarboxylase (ODC)
- ABC-family proteins mediated transport
- AUF1 (hnRNP D0) binds and destabilizes mRNA
- Asymmetric localization of PCP proteins
- Degradation of AXIN
- Degradation of DVL
- Hedgehog ligand biogenesis
- Hh mutants are degraded by ERAD
- Dectin-1 mediated noncanonical NF-kB signaling
- CLEC7A (Dectin-1) signaling
- Degradation of GLI1 by the proteasome
- Degradation of GLI2 by the proteasome
- GLI3 is processed to GLI3R by the proteasome
- Hedgehog 'on' state
- Regulation of RAS by GAPs
- TNFR2 non-canonical NF-kB pathway
- NIK-->noncanonical NF-kB signaling
- Defective CFTR causes cystic fibrosis
- MAPK6/MAPK4 signaling
- UCH proteinases
- Ub-specific processing proteases
- Assembly of the pre-replicative complex
- Orc1 removal from chromatin
- CDK-mediated phosphorylation and removal of Cdc6
- G2/M Checkpoints
- Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A
- Ubiquitin-dependent degradation of Cyclin D
- The role of GTSE1 in G2/M progression after G2 checkpoint
- FBXL7 down-regulates AURKA during mitotic entry and in early mitosis
- RUNX1 regulates transcription of genes involved in differentiation of HSCs
- Regulation of RUNX2 expression and activity
- Regulation of RUNX2 expression and activity
- Regulation of RUNX3 expression and activity
- Regulation of PTEN stability and activity
- Neddylation
- Regulation of expression of SLITs and ROBOs
- Interleukin-1 signaling
- Negative regulation of NOTCH4 signaling
- KEAP1-NFE2L2 pathway
- GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2
- Degradation of CDH1
- Somitogenesis
- Antigen processing: Ubiquitination & Proteasome degradation
- Proteasome assembly
- Proteasome assembly
- GSK3B-mediated proteasomal degradation of PD-L1(CD274)
- SPOP-mediated proteasomal degradation of PD-L1(CD274)
- AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274)
- Degradation of CRY and PER proteins
- Degradation of CRY and PER proteins
- Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide
- Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide
|
|
|
| Novel |
SLC22A4
|
solute carrier family 22 member 4 |
- SLC-mediated transport of organic cations
|
|
|
|
ADIPOQ
|
adiponectin, C1Q and collagen domain containing |
- AMPK inhibits chREBP transcriptional activation activity
- Transcriptional regulation of white adipocyte differentiation
- MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
|
|
|
|
ANKRD46
|
ankyrin repeat domain 46 |
|
|
|
|
AP1M2
|
adaptor related protein complex 1 subunit mu 2 |
- Nef mediated downregulation of MHC class I complex cell surface expression
- MHC class II antigen presentation
- Lysosome Vesicle Biogenesis
- Golgi Associated Vesicle Biogenesis
|
|
|
|
AQP10
|
aquaporin 10 |
- Passive transport by Aquaporins
|
|
|
|
BRICD5
|
BRICHOS domain containing 5 |
|
|
|
|
C3orf52
|
chromosome 3 open reading frame 52 |
|
|
|
|
CD226
|
CD226 molecule |
- Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
|
|
|
|
CD47
|
CD47 molecule |
- Cell surface interactions at the vascular wall
- Integrin cell surface interactions
- Signal regulatory protein family interactions
- Signal regulatory protein family interactions
- Neutrophil degranulation
|
|
|
|
CD96
|
CD96 molecule |
- Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
|
|
- C syndrome, including: Opitz trigonocephaly syndrome; Bohring-Opitz syndrome (BOPS)
|
|
CLDN19
|
claudin 19 |
- Tight junction interactions
|
|
|
|
CTXN3
|
cortexin 3 |
|
|
|
|
CYB561A3
|
cytochrome b561 family member A3 |
|
|
|