| Novel |
AKAP1
|
A-kinase anchoring protein 1 |
- Mitochondrial calcium ion transport
- Factors involved in megakaryocyte development and platelet production
|
|
|
| Novel |
BFAR
|
bifunctional apoptosis regulator |
|
|
|
| Novel |
CD46
|
CD46 molecule |
- Regulation of Complement cascade
|
|
|
| Novel |
ELL
|
elongation factor for RNA polymerase II |
- Formation of RNA Pol II elongation complex
- Formation of HIV elongation complex in the absence of HIV Tat
- Formation of HIV-1 elongation complex containing HIV-1 Tat
- Pausing and recovery of Tat-mediated HIV elongation
- Tat-mediated HIV elongation arrest and recovery
- Tat-mediated elongation of the HIV-1 transcript
- HIV elongation arrest and recovery
- Pausing and recovery of HIV elongation
- RNA Polymerase II Pre-transcription Events
- Transcription-Coupled Nucleotide Excision Repair (TC-NER)
- TP53 Regulates Transcription of DNA Repair Genes
- RNA polymerase II transcribes snRNA genes
- RNA polymerase II transcribes snRNA genes
- RNA Polymerase II Transcription Elongation
|
|
|
| Novel |
MECP2
|
methyl-CpG binding protein 2 |
|
|
- Non-syndromic X-linked mental retardation
- Prader-Willi and Angelman syndromes, including: Angelman syndrome (AS); Prader-Willi syndrome (PWS)
- Rett syndrome
|
| Novel |
PRKCA
|
protein kinase C alpha |
- Calmodulin induced events
- Disinhibition of SNARE formation
- SHC1 events in ERBB2 signaling
- Signaling by SCF-KIT
- Regulation of KIT signaling
- EGFR Transactivation by Gastrin
- Inactivation, recovery and regulation of the phototransduction cascade
- Syndecan interactions
- Acetylcholine regulates insulin secretion
- Ca2+ pathway
- Trafficking of GluR2-containing AMPA receptors
- G alpha (z) signalling events
- Depolymerization of the Nuclear Lamina
- HuR (ELAVL1) binds and stabilizes mRNA
- WNT5A-dependent internalization of FZD4
- VEGFR2 mediated cell proliferation
- RHO GTPases Activate NADPH Oxidases
- Response to elevated platelet cytosolic Ca2+
- RET signaling
- ROBO receptors bind AKAP5
- ROBO receptors bind AKAP5
|
- Phosphatidyl serine
- Vitamin E
- Tamoxifen
- Staurosporine
- Dequalinium
- Ingenol mebutate
- Aprinocarsen
- Midostaurin
- Perifosine
- Ellagic acid
- Benzoyl peroxide
- Bryostatin 1
- alpha-Tocopherol succinate
- D-alpha-Tocopherol acetate
|
|
| Novel |
RAB8A
|
RAB8A, member RAS oncogene family |
- Translocation of SLC2A4 (GLUT4) to the plasma membrane
- Regulation of PLK1 Activity at G2/M Transition
- Anchoring of the basal body to the plasma membrane
- VxPx cargo-targeting to cilium
- TBC/RABGAPs
- RAB geranylgeranylation
- RAB GEFs exchange GTP for GDP on RABs
|
|
|
| Novel |
RALBP1
|
ralA binding protein 1 |
- CDC42 GTPase cycle
- RAC1 GTPase cycle
|
|
|
| Novel |
RANGAP1
|
Ran GTPase activating protein 1 |
- Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
- Rev-mediated nuclear export of HIV RNA
- Separation of Sister Chromatids
- Resolution of Sister Chromatid Cohesion
- SUMOylation of DNA replication proteins
- RHO GTPases Activate Formins
- Mitotic Prometaphase
- Postmitotic nuclear pore complex (NPC) reformation
- EML4 and NUDC in mitotic spindle formation
- SUMOylation of nuclear envelope proteins
|
|
|
| Novel |
RFX1
|
regulatory factor X1 |
|
|
|
| Novel |
TCF4
|
transcription factor 4 |
- Myogenesis
- Myogenesis
- TGFBR3 expression
|
|
- Pitt-Hopkins syndrome, including: Pitt-Hopkins syndrome; Pitt-Hopkins-like syndrome
|
| Novel |
TPM4
|
tropomyosin 4 |
- Striated Muscle Contraction
- Smooth Muscle Contraction
- RHOV GTPase cycle
- Signaling by ALK fusions and activated point mutants
|
|
|
| Novel |
UTRN
|
utrophin |
- EGR2 and SOX10-mediated initiation of Schwann cell myelination
- Formation of the dystrophin-glycoprotein complex (DGC)
- Formation of the dystrophin-glycoprotein complex (DGC)
|
- Zinc
- Zinc acetate
- Zinc chloride
- Zinc sulfate, unspecified form
|
|
| Novel |
ZNF208
|
zinc finger protein 208 |
- Generic Transcription Pathway
|
|
|
|
AANAT
|
aralkylamine N-acetyltransferase |
- Serotonin and melatonin biosynthesis
|
- CoA-S-trimethylene-acetyl-tryptamine
- CoA-s-acetyl tryptamine
- CoA-S-acetyl 5-bromotryptamine
- Cannabidiol
- Medical Cannabis
- Nabiximols
|
- Delayed sleep phase syndrome
|
|
ABCA1
|
ATP binding cassette subfamily A member 1 |
- PPARA activates gene expression
- Defective ABCA1 causes TGD
- HDL assembly
- NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
|
|
- Tangier disease
- Hypoalphalipoproteinemia
|
|
ACLY
|
ATP citrate lyase |
- ChREBP activates metabolic gene expression
- Neutrophil degranulation
- Fatty acyl-CoA biosynthesis
|
|
|
|
ADCY5
|
adenylate cyclase 5 |
- Glucagon signaling in metabolic regulation
- PKA activation
- PKA activation in glucagon signalling
- Adenylate cyclase activating pathway
- Adenylate cyclase inhibitory pathway
- Adenylate cyclase inhibitory pathway
- Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
- Adrenaline,noradrenaline inhibits insulin secretion
- G alpha (s) signalling events
- G alpha (s) signalling events
- G alpha (i) signalling events
- G alpha (z) signalling events
- G alpha (z) signalling events
- Vasopressin regulates renal water homeostasis via Aquaporins
- Hedgehog 'off' state
- GPER1 signaling
- GPER1 signaling
- ADORA2B mediated anti-inflammatory cytokines production
- ADORA2B mediated anti-inflammatory cytokines production
- FCGR3A-mediated IL10 synthesis
- High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells
|
- Colforsin
- Colforsin
- 2',5'-DIDEOXY-ADENOSINE 3'-MONOPHOSPHATE
- Aurothioglucose
|
|
|
ADD1
|
adducin 1 |
- Caspase-mediated cleavage of cytoskeletal proteins
- XBP1(S) activates chaperone genes
- Miscellaneous transport and binding events
|
|
|
|
ADD2
|
adducin 2 |
- Miscellaneous transport and binding events
|
|
|