| Novel |
CTRL
|
chymotrypsin like |
- Developmental Lineage of Pancreatic Acinar Cells
|
|
|
| Novel |
FCSK
|
fucose kinase |
|
|
|
| Novel |
HPR
|
haptoglobin-related protein |
- Scavenging of heme from plasma
|
|
|
| Novel |
ZFHX3
|
zinc finger homeobox 3 |
- RUNX3 regulates CDKN1A transcription
|
|
|
|
APP
|
amyloid beta precursor protein |
- Platelet degranulation
- ECM proteoglycans
- Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
- G alpha (q) signalling events
- G alpha (i) signalling events
- Lysosome Vesicle Biogenesis
- Formyl peptide receptors bind formyl peptides and many other ligands
- TAK1-dependent IKK and NF-kappa-B activation
- The NLRP3 inflammasome
- Advanced glycosylation endproduct receptor signaling
- Advanced glycosylation endproduct receptor signaling
- Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
- Post-translational protein phosphorylation
- TRAF6 mediated NF-kB activation
- Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
- Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
- Purinergic signaling in leishmaniasis infection
- Amyloid fiber formation
|
- Deferoxamine
- Aluminium
- Zinc
- L-methionine (R)-S-oxide
- Resveratrol
- Tromethamine
- Phenserine
- Tetrathiomolybdate
- CAD106
- Mito-4509
- Edonerpic
- Dimercaprol
- Copper
- Florbetaben (18F)
- Florbetapir (18F)
- Flutemetamol (18F)
- Gantenerumab
- Aducanumab
- Zinc acetate
- Aluminium phosphate
- Aluminum acetate
- Zinc chloride
- Zinc sulfate, unspecified form
- Lecanemab
|
|
|
BRCA2
|
BRCA2 DNA repair associated |
- HDR through MMEJ (alt-NHEJ)
- HDR through Homologous Recombination (HRR)
- Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)
- Resolution of D-loop Structures through Holliday Junction Intermediates
- Homologous DNA Pairing and Strand Exchange
- Presynaptic phase of homologous DNA pairing and strand exchange
- Meiotic recombination
- Defective homologous recombination repair (HRR) due to BRCA1 loss of function
- Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function
- Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function
- Impaired BRCA2 translocation to the nucleus
- Impaired BRCA2 binding to RAD51
- Impaired BRCA2 binding to PALB2
- Impaired BRCA2 binding to SEM1 (DSS1)
|
|
- Ovarian cancer
- Fanconi anemia
- Breast cancer
- Pancreatic cancer
|
|
DMTN
|
dematin actin binding protein |
- Miscellaneous transport and binding events
|
|
|
|
GAA
|
alpha glucosidase |
- Glycogen storage disease type II (GAA)
- Neutrophil degranulation
- Glycogen breakdown (glycogenolysis)
|
- Acarbose
- Miglitol
- AT2220
- alpha-Arbutin
|
- Glycogen storage diseases (GSD), including: von Gierke disease (GSD type Ia); Pompe disease (GSD type II); Cori disease, Forbe disease (GSD type III); Andersen disease (GSD type IV); McArdle disease (GSD type V); Hers disease (GSD type VI); Tarui disease (GSD type VII); Phosphorylase kinase deficiency (GSD type IX); Fanconi-Bickel syndrome (GSD type XI); Glycogen synthase deficiency (GSD type 0)
|
|
LINC00632
|
long intergenic non-protein coding RNA 632 |
|
|
|
|
OGT
|
O-linked N-acetylglucosamine (GlcNAc) transferase |
- HATs acetylate histones
- RIPK1-mediated regulated necrosis
- Regulation of necroptotic cell death
- UCH proteinases
- Formation of WDR5-containing histone-modifying complexes
|
|
|