| Novel |
B3GNT9
|
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 |
- O-linked glycosylation of mucins
|
|
|
| Novel |
CENPT
|
centromere protein T |
- Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
- Separation of Sister Chromatids
- Resolution of Sister Chromatid Cohesion
- RHO GTPases Activate Formins
- Deposition of new CENPA-containing nucleosomes at the centromere
- Mitotic Prometaphase
- EML4 and NUDC in mitotic spindle formation
|
|
|
| Novel |
COG8
|
component of oligomeric golgi complex 8 |
- COPI-mediated anterograde transport
- Intra-Golgi traffic
- Retrograde transport at the Trans-Golgi-Network
|
|
- Congenital disorders of glycosylation (CDG) type II
|
| Novel |
ESRP2
|
epithelial splicing regulatory protein 2 |
- FGFR2 alternative splicing
|
|
|
| Novel |
PHAF1
|
phagophore assembly factor 1 |
|
|
|
| Novel |
RPS2P45
|
ribosomal protein S2 pseudogene 45 |
|
|
|
| Novel |
SLC7A6OS
|
solute carrier family 7 member 6 opposite strand |
|
|
|
|
AHNAK2
|
AHNAK nucleoprotein 2 |
|
|
|
|
APP
|
amyloid beta precursor protein |
- Platelet degranulation
- ECM proteoglycans
- Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
- G alpha (q) signalling events
- G alpha (i) signalling events
- Lysosome Vesicle Biogenesis
- Formyl peptide receptors bind formyl peptides and many other ligands
- TAK1-dependent IKK and NF-kappa-B activation
- The NLRP3 inflammasome
- Advanced glycosylation endproduct receptor signaling
- Advanced glycosylation endproduct receptor signaling
- Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
- Post-translational protein phosphorylation
- TRAF6 mediated NF-kB activation
- Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
- Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
- Purinergic signaling in leishmaniasis infection
- Amyloid fiber formation
|
- Deferoxamine
- Aluminium
- Zinc
- L-methionine (R)-S-oxide
- Resveratrol
- Tromethamine
- Phenserine
- Tetrathiomolybdate
- CAD106
- Mito-4509
- Edonerpic
- Dimercaprol
- Copper
- Florbetaben (18F)
- Florbetapir (18F)
- Flutemetamol (18F)
- Gantenerumab
- Aducanumab
- Zinc acetate
- Aluminium phosphate
- Aluminum acetate
- Zinc chloride
- Zinc sulfate, unspecified form
- Lecanemab
|
|
|
AQP6
|
aquaporin 6 |
- Passive transport by Aquaporins
|
|
|
|
BIK
|
BCL2 interacting killer |
|
|
|
|
BNIP3L
|
BCL2 interacting protein 3 like |
- TP53 Regulates Transcription of Genes Involved in Cytochrome C Release
|
|
|
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BTNL9
|
butyrophilin like 9 |
- Butyrophilin (BTN) family interactions
|
|
|
|
CD33
|
CD33 molecule |
- Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
- Neutrophil degranulation
|
- Gemtuzumab ozogamicin
- AVE9633
|
|
|
CD79A
|
CD79a molecule |
- CD22 mediated BCR regulation
- Potential therapeutics for SARS
- Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
- Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
|
|
- Agammaglobulinemias, including the following six diseases: X-linked agammaglobulinemia (Bruton's agammaglobulinemia, XLA); IgM heavy chain gene deletions; Ig-alpha defect; Autosomal recessive agammaglobulinaemia; B cell-linker protein (BLNK) deficiency; Leucine-rich repeat-containing 8
|
|
CGRRF1
|
cell growth regulator with ring finger domain 1 |
|
|
|
|
CLDN7
|
claudin 7 |
- Tight junction interactions
|
|
|
|
CLN8
|
CLN8 transmembrane ER and ERGIC protein |
|
|
- Progressive myoclonic epilepsy (PME), including: Lafora disease (LBD); Unverricht-Lundborg disease (ULD); Neuronal ceroid lipofuscinoses (NCL); Type I sialidosis; Action myoclonus-renal failure syndrome (AMRF); Type III Gaucher disease (GD)
- Neuronal ceroid lipofuscinosis, including: Infantile Neuronal Ceroid Lipofuscinosis (INCL)/ Santavuori-Haltia Disease (CLN1); Late-Infantile Neuronal Ceroid Lipofuscinosis (LINCL)/ Jansky-Bielschowsky Disease (CLN2); Juvenile Neuronal Ceroid Lipofuscinosis (JNCL)/Batten Disease/ Spielmeyer-Vogt Disease (CLN3); Adult Neuronal Ceroid Lipofuscinosis (ANCL)/ Kufs Disease (CLN4); LINCL variant (CLN5, CLN6, CLN7, CLN8); Batten Disease variant (CLN9); Congenital NCL (CLN10)
|
|
CPLX4
|
complexin 4 |
|
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|
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CREB3
|
cAMP responsive element binding protein 3 |
- CREB3 factors activate genes
- CREB3 factors activate genes
|
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