| Novel |
ATP6V0B
|
ATPase H+ transporting V0 subunit b |
- ROS and RNS production in phagocytes
- Insulin receptor recycling
- Transferrin endocytosis and recycling
- Amino acids regulate mTORC1
- Ion channel transport
- Regulation of MITF-M-dependent genes involved in lysosome biogenesis and autophagy
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| Novel |
B4GALT1
|
beta-1,4-galactosyltransferase 1 |
- Pre-NOTCH Processing in Golgi
- Keratan sulfate biosynthesis
- Interaction With Cumulus Cells And The Zona Pellucida
- Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)
- Defective B4GALT1 causes CDG-2d
- Lactose synthesis
- Neutrophil degranulation
- N-Glycan antennae elongation
|
- N-Acetylglucosamine
- 6-Aminohexyl-uridine-C1,5'-diphosphate
- 4)-N-acetyl-beta-D-glucosamine
- Galactose-uridine-5'-diphosphate
- Uridine monophosphate
- 2-(N-morpholino)ethanesulfonic acid
|
- Congenital disorders of glycosylation (CDG) type II
|
| Novel |
CNTFR
|
ciliary neurotrophic factor receptor |
- IL-6-type cytokine receptor ligand interactions
|
|
|
| Novel |
DCTN3
|
dynactin subunit 3 |
- MHC class II antigen presentation
- Regulation of PLK1 Activity at G2/M Transition
- HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
- Loss of Nlp from mitotic centrosomes
- Recruitment of mitotic centrosome proteins and complexes
- Loss of proteins required for interphase microtubule organization from the centrosome
- Recruitment of NuMA to mitotic centrosomes
- Anchoring of the basal body to the plasma membrane
- COPI-mediated anterograde transport
- COPI-independent Golgi-to-ER retrograde traffic
- AURKA Activation by TPX2
|
|
|
| Novel |
FZD7
|
frizzled class receptor 7 |
- Class B/2 (Secretin family receptors)
- PCP/CE pathway
- PCP/CE pathway
- Asymmetric localization of PCP proteins
- WNT5:FZD7-mediated leishmania damping
- WNT5:FZD7-mediated leishmania damping
|
|
|
| Novel |
GALT
|
galactose-1-phosphate uridylyltransferase |
- Defective GALT can cause GALCT
- Galactose catabolism
|
|
|
| Novel |
PAX5
|
paired box 5 |
- RUNX1 regulates transcription of genes involved in BCR signaling
|
|
- Lymphoplasmacytic lymphoma
|
| Novel |
PPM1E
|
protein phosphatase, Mg2+/Mn2+ dependent 1E |
- Negative regulation of NMDA receptor-mediated neuronal transmission
|
|
|
| Novel |
RPS4X
|
ribosomal protein S4 X-linked |
- L13a-mediated translational silencing of Ceruloplasmin expression
- Peptide chain elongation
- SRP-dependent cotranslational protein targeting to membrane
- SRP-dependent cotranslational protein targeting to membrane
- Viral mRNA Translation
- Selenocysteine synthesis
- Major pathway of rRNA processing in the nucleolus and cytosol
- Translation initiation complex formation
- Formation of a pool of free 40S subunits
- Formation of the ternary complex, and subsequently, the 43S complex
- Ribosomal scanning and start codon recognition
- GTP hydrolysis and joining of the 60S ribosomal subunit
- Eukaryotic Translation Termination
- Regulation of expression of SLITs and ROBOs
- Response of EIF2AK4 (GCN2) to amino acid deficiency
- SARS-CoV-1 modulates host translation machinery
- SARS-CoV-2 modulates host translation machinery
- Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
- Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
- PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA
- ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA
|
|
|
| Novel |
TLN1
|
talin 1 |
- Platelet degranulation
- Integrin signaling
- GRB2:SOS provides linkage to MAPK signaling for Integrins
- p130Cas linkage to MAPK signaling for integrins
- XBP1(S) activates chaperone genes
- SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
- Smooth Muscle Contraction
- MAP2K and MAPK activation
- Signaling by moderate kinase activity BRAF mutants
- Signaling by high-kinase activity BRAF mutants
- Signaling by BRAF and RAF1 fusions
- Paradoxical activation of RAF signaling by kinase inactive BRAF
- Signaling downstream of RAS mutants
- Signaling by RAF1 mutants
- High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells
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|
|
ACKR2
|
atypical chemokine receptor 2 |
- Chemokine receptors bind chemokines
|
|
|
|
ACKR4
|
atypical chemokine receptor 4 |
- Chemokine receptors bind chemokines
|
|
|
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CCL22
|
C-C motif chemokine ligand 22 |
- Chemokine receptors bind chemokines
- Interleukin-10 signaling
- Interleukin-4 and Interleukin-13 signaling
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|
|
|
CCR10
|
C-C motif chemokine receptor 10 |
- Chemokine receptors bind chemokines
- G alpha (i) signalling events
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|
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CCR7
|
C-C motif chemokine receptor 7 |
- Chemokine receptors bind chemokines
- G alpha (i) signalling events
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|
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CXCL13
|
C-X-C motif chemokine ligand 13 |
- Chemokine receptors bind chemokines
- G alpha (i) signalling events
|
|
|
|
MEOX2
|
mesenchyme homeobox 2 |
|
|
|
|
PF4V1
|
platelet factor 4 variant 1 |
- Common Pathway of Fibrin Clot Formation
- Cell surface interactions at the vascular wall
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