SRPK2 - New-wiki

Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
HMGN2	high mobility group nucleosomal binding domain 2
HMGN3	high mobility group nucleosomal binding domain 3
HMGXB4	HMG-box containing 4
HNRNPA1	heterogeneous nuclear ribonucleoprotein A1	FGFR2 alternative splicing mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA SARS-CoV-1-host interactions SARS-CoV-1 modulates host translation machinery
HNRNPA3	heterogeneous nuclear ribonucleoprotein A3	mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA
HNRNPC	heterogeneous nuclear ribonucleoprotein C	SUMOylation of RNA binding proteins mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA RHOBTB2 GTPase cycle RHOBTB1 GTPase cycle
HNRNPK	heterogeneous nuclear ribonucleoprotein K	SUMOylation of RNA binding proteins mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA HCMV Late Events	Artenimol Phenethyl Isothiocyanate
HOMER3	homer scaffold protein 3	Neurexins and neuroligins Neurexins and neuroligins
HOXB6	homeobox B6
HTATSF1	HIV-1 Tat specific factor 1	mRNA Splicing - Major Pathway
IFIT5	interferon induced protein with tetratricopeptide repeats 5	Interferon alpha/beta signaling
IRS2	insulin receptor substrate 2	PI3K Cascade IRS-mediated signalling SOS-mediated signalling SOS-mediated signalling PIP3 activates AKT signaling Interleukin-7 signaling PI3K/AKT activation PI3K/AKT activation Constitutive Signaling by Aberrant PI3K in Cancer IRS-related events triggered by IGF1R Signaling by Leptin RAF/MAP kinase cascade PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling IRS activation Signal attenuation RET signaling Signaling by Erythropoietin Signaling by Erythropoietin Erythropoietin activates Phosphoinositide-3-kinase (PI3K) Erythropoietin activates Phosphoinositide-3-kinase (PI3K) Erythropoietin activates Phospholipase C gamma (PLCG) Erythropoietin activates STAT5 Erythropoietin activates RAS Erythropoietin activates RAS Growth hormone receptor signaling
ISLR	immunoglobulin superfamily containing leucine rich repeat	Platelet degranulation
JMJD1C	jumonji domain containing 1C	Factors involved in megakaryocyte development and platelet production
KANK2	KN motif and ankyrin repeat domains 2
KCNN2	potassium calcium-activated channel subfamily N member 2	Ca2+ activated K+ channels Acetylcholine inhibits contraction of outer hair cells	Procaine Ritodrine Nitrendipine Miconazole Colforsin Trimebutine Rimtuzalcap
KHDRBS1	KH RNA binding domain containing, signal transduction associated 1	PTK6 Regulates Proteins Involved in RNA Processing
KIF11	kinesin family member 11	MHC class II antigen presentation COPI-dependent Golgi-to-ER retrograde traffic Kinesins	3-[(5s)-1-Acetyl-3-(2-Chlorophenyl)-4,5-Dihydro-1h-Pyrazol-5-Yl]Phenol Monastrol Filanesib (4R)-4-(3-HYDROXYPHENYL)-N,N,7,8-TETRAMETHYL-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXAMIDE N,N-DIETHYL-2-[(2-THIENYLCARBONYL)AMINO]-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE (5R)-N,N-DIETHYL-5-METHYL-2-[(THIOPHEN-2-YLCARBONYL)AMINO]-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE MK-0731 [(4R)-4-(3-HYDROXYPHENYL)-1,6-DIMETHYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDIN-5-YL](PHENYL)METHANONE (2S)-4-(2,5-DIFLUOROPHENYL)-N-METHYL-2-PHENYL-N-PIPERIDIN-4-YL-2,5-DIHYDRO-1H-PYRROLE-1-CARBOXAMIDE (1S)-1-CYCLOPROPYL-2-[(2S)-4-(2,5-DIFLUOROPHENYL)-2-PHENYL-2,5-DIHYDRO-1H-PYRROL-1-YL]-2-OXOETHANAMINE (2S)-4-(2,5-DIFLUOROPHENYL)-N,N-DIMETHYL-2-PHENYL-2,5-DIHYDRO-1H-PYRROLE-1-CARBOXAMIDE (5S)-5-(3-AMINOPROPYL)-3-(2,5-DIFLUOROPHENYL)-N-ETHYL-5-PHENYL-4,5-DIHYDRO-1H-PYRAZOLE-1-CARBOXAMIDE
KRT78	keratin 78	Keratinization Formation of the cornified envelope Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
LBR	lamin B receptor	Cholesterol biosynthesis Initiation of Nuclear Envelope (NE) Reformation RHOA GTPase cycle RHOC GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOD GTPase cycle RHOG GTPase cycle RAC3 GTPase cycle Regulation of MECP2 expression and activity		HEM skeletal dysplasia; Greenberg dysplasia Pelger-Huet anomaly

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