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TLR3
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toll like receptor 3 |
- Trafficking and processing of endosomal TLR
- Toll Like Receptor 3 (TLR3) Cascade
- TICAM1, RIP1-mediated IKK complex recruitment
- RIP-mediated NFkB activation via ZBP1
- TLR3 deficiency - HSE
- UNC93B1 deficiency - HSE
- TICAM1 deficiency - HSE
- TRAF3 deficiency - HSE
- TLR3-mediated TICAM1-dependent programmed cell death
- TICAM1-dependent activation of IRF3/IRF7
- TICAM1,TRAF6-dependent induction of TAK1 complex
- Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation
- RSV-host interactions
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TNFAIP3
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TNF alpha induced protein 3 |
- NOD1/2 Signaling Pathway
- TNFR1-induced proapoptotic signaling
- Regulation of TNFR1 signaling
- TNFR1-induced NF-kappa-B signaling pathway
- Ovarian tumor domain proteases
- Negative regulators of DDX58/IFIH1 signaling
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TNFRSF11A
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TNF receptor superfamily member 11a |
- TNFR2 non-canonical NF-kB pathway
- TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
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- Osteopetrosis, including: Osteopetrosis, severe neonatal or infantile forms; Osteopetrosis, intermediate forms; Osteopetrosis with renal tubular acidosis; Osteopetrosis, late-onset form type 1; Osteopetrosis, late-onset form type 2; Osteopetrosis, osteoclast poor
- Paget's disease of bone and related disorders, including: ; Paget's disease of bone (PDB); Familial expansile osteolysis (FEO); Early-onset Paget's disease of bone (PDB2); Expansile skeletal hyperphosphatasia (ESH); Juvenile Paget's disease (JPD)
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TNFRSF13B
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TNF receptor superfamily member 13B |
- TNFs bind their physiological receptors
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- Common variable immunodeficiency (CVID), including the following four diseases: Inducible T Cell costimulator (ICOS) defect; TACI defect; CD19 defect; BAFFR defect
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TNFRSF19
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TNF receptor superfamily member 19 |
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TNFSF11
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TNF superfamily member 11 |
- TNFR2 non-canonical NF-kB pathway
- TNFs bind their physiological receptors
- TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
- Transcriptional and post-translational regulation of MITF-M expression and activity
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- Lenalidomide
- AMGN-0007
- Denosumab
- Thiocolchicoside
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- Osteopetrosis, including: Osteopetrosis, severe neonatal or infantile forms; Osteopetrosis, intermediate forms; Osteopetrosis with renal tubular acidosis; Osteopetrosis, late-onset form type 1; Osteopetrosis, late-onset form type 2; Osteopetrosis, osteoclast poor
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TRAF1
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TNF receptor associated factor 1 |
- Regulation of TNFR1 signaling
- TNFR1-induced NF-kappa-B signaling pathway
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TRAF2
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TNF receptor associated factor 2 |
- Caspase activation via Death Receptors in the presence of ligand
- Regulation by c-FLIP
- RIPK1-mediated regulated necrosis
- CASP8 activity is inhibited
- TNFR1-induced proapoptotic signaling
- Regulation of TNFR1 signaling
- TNFR1-induced NF-kappa-B signaling pathway
- TNFR2 non-canonical NF-kB pathway
- Regulation of necroptotic cell death
- TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
- Ub-specific processing proteases
- Dimerization of procaspase-8
- TNF signaling
- TRAF6 mediated IRF7 activation
- TRAF6 mediated NF-kB activation
- TRAF6 mediated NF-kB activation
- Defective RIPK1-mediated regulated necrosis
- Regulation of NF-kappa B signaling
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TRAF3IP1
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TRAF3 interacting protein 1 |
- Intraflagellar transport
- Intraflagellar transport
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TRAF3IP2
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TRAF3 interacting protein 2 |
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TRAF4
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TNF receptor associated factor 4 |
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TRAF5
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TNF receptor associated factor 5 |
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TRAF7
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TNF receptor associated factor 7 |
- Antigen processing: Ubiquitination & Proteasome degradation
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TRAFD1
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TRAF-type zinc finger domain containing 1 |
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TRAM1
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translocation associated membrane protein 1 |
- SRP-dependent cotranslational protein targeting to membrane
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TRIM17
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tripartite motif containing 17 |
- Interferon gamma signaling
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TRIM25
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tripartite motif containing 25 |
- ISG15 antiviral mechanism
- DDX58/IFIH1-mediated induction of interferon-alpha/beta
- Termination of translesion DNA synthesis
- Ovarian tumor domain proteases
- Interferon gamma signaling
- TRAF3-dependent IRF activation pathway
- TRAF6 mediated IRF7 activation
- TRAF6 mediated NF-kB activation
- TRAF6 mediated NF-kB activation
- NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
- Negative regulators of DDX58/IFIH1 signaling
- Negative regulators of DDX58/IFIH1 signaling
- SARS-CoV-1 activates/modulates innate immune responses
- SARS-CoV-2 activates/modulates innate and adaptive immune responses
- Evasion by RSV of host interferon responses
- RSV-host interactions
- PKR-mediated signaling
- Modulation of host responses by IFN-stimulated genes
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TRIM37
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tripartite motif containing 37 |
- Antigen processing: Ubiquitination & Proteasome degradation
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TTC3
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tetratricopeptide repeat domain 3 |
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TXNIP
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thioredoxin interacting protein |
- The NLRP3 inflammasome
- The NLRP3 inflammasome
- Regulation of FOXO transcriptional activity by acetylation
- Purinergic signaling in leishmaniasis infection
- Purinergic signaling in leishmaniasis infection
- Cytoprotection by HMOX1
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