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EPS8L1 |
EPS8 signaling adaptor L1 |
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EPS8L3 |
EPS8 signaling adaptor L3 |
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ERBB3 |
erb-b2 receptor tyrosine kinase 3 |
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- Type I diabetes mellitus
- Lethal congenital contractural syndrome (LCCS)
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ERC1 |
ELKS/RAB6-interacting/CAST family member 1 |
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ERCC3 |
ERCC excision repair 3, TFIIH core complex helicase subunit |
- Formation of RNA Pol II elongation complex
- Formation of the Early Elongation Complex
- Formation of HIV elongation complex in the absence of HIV Tat
- Formation of the HIV-1 Early Elongation Complex
- RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
- HIV Transcription Initiation
- RNA Polymerase II HIV Promoter Escape
- Transcription of the HIV genome
- Formation of HIV-1 elongation complex containing HIV-1 Tat
- Tat-mediated elongation of the HIV-1 transcript
- NoRC negatively regulates rRNA expression
- Formation of Incision Complex in GG-NER
- Dual Incision in GG-NER
- RNA Polymerase II Pre-transcription Events
- Formation of TC-NER Pre-Incision Complex
- Transcription-Coupled Nucleotide Excision Repair (TC-NER)
- Dual incision in TC-NER
- Gap-filling DNA repair synthesis and ligation in TC-NER
- TP53 Regulates Transcription of DNA Repair Genes
- mRNA Capping
- RNA Polymerase I Transcription Initiation
- RNA Polymerase I Promoter Escape
- RNA Polymerase II Promoter Escape
- RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
- RNA Polymerase I Transcription Termination
- RNA Polymerase II Transcription Initiation
- RNA Polymerase II Transcription Elongation
- RNA Polymerase II Transcription Initiation And Promoter Clearance
- RNA Pol II CTD phosphorylation and interaction with CE
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- Disorders of nucleotide excision repair, including: Xeroderma pigmentosum (XP); Cockayne syndrome (CS); UV-sensitive syndrome (UVS); Trichothiodystrophy (TTD); Cerebro-oculo-facio-skeletal syndrome (COFS); XFE progeroid syndrome
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ERN1 |
endoplasmic reticulum to nucleus signaling 1 |
- IRE1alpha activates chaperones
- IRE1alpha activates chaperones
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- N~2~-1H-benzimidazol-5-yl-N~4~-(3-cyclopropyl-1H-pyrazol-5-yl)pyrimidine-2,4-diamine
- Fostamatinib
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EVI5L |
ecotropic viral integration site 5 like |
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EXOSC8 |
exosome component 8 |
- ATF4 activates genes in response to endoplasmic reticulum stress
- mRNA decay by 3' to 5' exoribonuclease
- Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
- Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA
- KSRP (KHSRP) binds and destabilizes mRNA
- Major pathway of rRNA processing in the nucleolus and cytosol
- Nuclear RNA decay
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F5 |
coagulation factor V |
- Platelet degranulation
- Common Pathway of Fibrin Clot Formation
- COPII-mediated vesicle transport
- Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
- Cargo concentration in the ER
- Post-translational protein phosphorylation
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- Drotrecogin alfa
- Thrombomodulin Alfa
- Thrombin
- Protein C
- Human thrombin
- Thrombin alfa
- Protein S human
- Anti-inhibitor coagulant complex
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- Factor V deficiency; Owren disease
- Inherited thrombophilia
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FAM43A |
family with sequence similarity 43 member A |
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FAM76B |
family with sequence similarity 76 member B |
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FAM90A1 |
family with sequence similarity 90 member A1 |
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FBXO24 |
F-box protein 24 |
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FCHO1 |
FCH and mu domain containing endocytic adaptor 1 |
- Cargo recognition for clathrin-mediated endocytosis
- Clathrin-mediated endocytosis
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FGF12 |
fibroblast growth factor 12 |
- Phase 0 - rapid depolarisation
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FGFR3 |
fibroblast growth factor receptor 3 |
- Signaling by activated point mutants of FGFR3
- t(4;14) translocations of FGFR3
- Signaling by FGFR3 in disease
- Signaling by FGFR3 fusions in cancer
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- XL999
- Pazopanib
- Ponatinib
- Lenvatinib
- Nintedanib
- Infigratinib
- Fostamatinib
- Erdafitinib
- Pemigatinib
- Futibatinib
- Selpercatinib
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- CATSHL syndrome
- Multiple myeloma
- FGFR3-related short limb skeletal dysplasias, including: Achondroplasia; Hypochondroplasia; Thanatophoric dysplasia, type 1; Thanatophoric dysplasia, type 2; Severe achondroplasia with developmental delay and acanthosis nigricans (SADDAN)
- Lacrimo-auriculo-dento-digital syndrome (LADD); Levy-Hollister syndrome
- Craniosynostosis, including: Pfeiffer syndrome; Apert syndrome; Crouzon syndrome; Jackson-Weiss syndrome; Beare-Stevenson syndrome; Muenke craniosynostosis; Saethre-Chotzen syndrome; Craniosynostosis Boston type; Antley-Bixler syndrome; Carpenter syndrome; Craniofrontonasal dysplasia; Noonan syndrome; Baller-Gerold syndrome
- Bladder cancer
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FIP1L1 |
factor interacting with PAPOLA and CPSF1 |
- Transport of Mature mRNA Derived from an Intronless Transcript
- mRNA 3'-end processing
- Processing of Capped Intron-Containing Pre-mRNA
- RNA Polymerase II Transcription Termination
- Processing of Intronless Pre-mRNAs
- Signaling by cytosolic PDGFRA and PDGFRB fusion proteins
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FMNL1 |
formin like 1 |
- RHO GTPases Activate Formins
- RHO GTPases Activate Formins
- CDC42 GTPase cycle
- RAC1 GTPase cycle
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FOXN3 |
forkhead box N3 |
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FXR1 |
FMR1 autosomal homolog 1 |
- Signaling by BRAF and RAF1 fusions
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