FXR1 - New-wiki

Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
FXR2	FMR1 autosomal homolog 2
GBP2	guanylate binding protein 2	Interferon gamma signaling Interferon alpha/beta signaling CASP4 inflammasome assembly Microbial factors inhibit CASP4 activity
GFAP	glial fibrillary acidic protein	Nuclear signaling by ERBB4 Chaperone Mediated Autophagy		Alexander disease
GLYR1	glyoxylate reductase 1 homolog
GOLGA2	golgin A2	Golgi Cisternae Pericentriolar Stack Reorganization Golgi Cisternae Pericentriolar Stack Reorganization COPII-mediated vesicle transport COPI-mediated anterograde transport Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
GOLGA3	golgin A3	RND2 GTPase cycle
GPSM2	G protein signaling modulator 2	G alpha (i) signalling events
GRIA2	glutamate ionotropic receptor AMPA type subunit 2	Activation of AMPA receptors Trafficking of GluR2-containing AMPA receptors Unblocking of NMDA receptors, glutamate binding and activation Unblocking of NMDA receptors, glutamate binding and activation MECP2 regulates neuronal receptors and channels Long-term potentiation	Glutamic acid Butabarbital Butalbital Talbutal Pentobarbital Secobarbital Metharbital Thiopental Primidone Methylphenobarbital Ethanol Phenobarbital Quinidine barbiturate Amobarbital Aprobarbital Butobarbital Heptabarbital Hexobarbital Barbital Dihydro-2-thioxo-5-((5-(2-(trifluoromethyl)phenyl)-2-furanyl)methyl)-4,6(1H,5H)-pyrimidinedione (S)-DES-ME-AMPA (S)-AMPA 2-Amino-3-(5-Tert-Butyl-3-(Phosphonomethoxy)-4-Isoxazolyl)Propionic Acid Iodo-Willardiine Fluoro-Willardiine Quisqualic acid (S)-2-Amino-3-(1,3,5,7-Pentahydro-2,4-Dioxo-Cyclopenta[E]Pyrimidin-1-Yl) Proionic Acid (2S)-2-Ammonio-3-[5-(2-methyl-2-propanyl)-3-oxido-1,2-oxazol-4-yl]propanoate FG-9041 Bromo-Willardiine Willardiine 2-Amino-3-(3-Hydroxy-7,8-Dihydro-6h-Cyclohepta[D]-4-Isoxazolyl)Propionic Acid Aniracetam THIO-ATPA Talampanel CX-717 N,N'-[biphenyl-4,4'-diyldi(2R)propane-2,1-diyl]dimethanesulfonamide 2,3,6A,7,8,9-HEXAHYDRO-11H-[1,4]DIOXINO[2,3-G]PYRROLO[2,1-B][1,3]BENZOXAZIN-11-ONE (3S)-3-cyclopentyl-6-methyl-7-[(4-methylpiperazin-1-yl)sulfonyl]-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide (3R)-3-cyclopentyl-7-[(4-methylpiperazin-1-yl)sulfonyl]-3,4-dihydro-2H-1,2-benzothiazine 1,1-dioxide (3R)-3-cyclopentyl-6-methyl-7-[(4-methylpiperazin-1-yl)sulfonyl]-3,4-dihydro-2H-1,2-benzothiazine 1,1-dioxide Fluciclovine (18F)
GRIP1	glutamate receptor interacting protein 1	Trafficking of GluR2-containing AMPA receptors
GRIP2	glutamate receptor interacting protein 2	Trafficking of GluR2-containing AMPA receptors
GRIPAP1	GRIP1 associated protein 1
HIVEP1	HIVEP zinc finger 1
HLA-DRB5	major histocompatibility complex, class II, DR beta 5	Downstream TCR signaling Phosphorylation of CD3 and TCR zeta chains Translocation of ZAP-70 to Immunological synapse Generation of second messenger molecules MHC class II antigen presentation Co-inhibition by PD-1 Interferon gamma signaling	1D09C3 Coccidioides immitis spherule
HMG20A	high mobility group 20A
HNRNPH2	heterogeneous nuclear ribonucleoprotein H2	mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA
HNRNPM	heterogeneous nuclear ribonucleoprotein M	FGFR2 alternative splicing mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA
HNRNPUL1	heterogeneous nuclear ribonucleoprotein U like 1
HOMER2	homer scaffold protein 2	Neurexins and neuroligins Neurexins and neuroligins
HOMER3	homer scaffold protein 3	Neurexins and neuroligins Neurexins and neuroligins
HSPB1	heat shock protein family B (small) member 1	VEGFA-VEGFR2 Pathway AUF1 (hnRNP D0) binds and destabilizes mRNA MAPK6/MAPK4 signaling Extra-nuclear estrogen signaling	Apatorsen Artenimol Phenethyl Isothiocyanate	Distal hereditary motor neuropathies (dHMN)

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