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PRKCZ
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protein kinase C zeta |
- GPVI-mediated activation cascade
- TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
- TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
- VEGFR2 mediated cell proliferation
- RHO GTPases Activate NADPH Oxidases
- Estrogen-stimulated signaling through PRKCZ
- Estrogen-stimulated signaling through PRKCZ
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- Tamoxifen
- Staurosporine
- Dequalinium
- Benzoyl peroxide
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PRKD1
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protein kinase D1 |
- Sphingolipid de novo biosynthesis
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- Bryostatin 1
- Fostamatinib
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PRRC2A
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proline rich coiled-coil 2A |
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SHANK3
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SH3 and multiple ankyrin repeat domains 3 |
- Neurexins and neuroligins
- Neurexins and neuroligins
- RET signaling
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SRSF1
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serine and arginine rich splicing factor 1 |
- Transport of Mature mRNA derived from an Intron-Containing Transcript
- mRNA Splicing - Major Pathway
- mRNA Splicing - Minor Pathway
- mRNA 3'-end processing
- Processing of Capped Intron-Containing Pre-mRNA
- RNA Polymerase II Transcription Termination
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SRSF9
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serine and arginine rich splicing factor 9 |
- Transport of Mature mRNA derived from an Intron-Containing Transcript
- mRNA Splicing - Major Pathway
- mRNA 3'-end processing
- Processing of Capped Intron-Containing Pre-mRNA
- RNA Polymerase II Transcription Termination
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TOP3B
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DNA topoisomerase III beta |
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ULK1
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unc-51 like autophagy activating kinase 1 |
- Macroautophagy
- Regulation of TNFR1 signaling
- TBC/RABGAPs
- RAB GEFs exchange GTP for GDP on RABs
- Receptor Mediated Mitophagy
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YWHAB
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tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta |
- Activation of BAD and translocation to mitochondria
- Translocation of SLC2A4 (GLUT4) to the plasma membrane
- MTOR signalling
- mTORC1-mediated signalling
- Frs2-mediated activation
- Frs2-mediated activation
- ARMS-mediated activation
- Signaling by Hippo
- Rap1 signalling
- Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
- Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA
- RHO GTPases activate PKNs
- TP53 Regulates Metabolic Genes
- RAF activation
- MAP2K and MAPK activation
- Negative regulation of MAPK pathway
- Signaling by moderate kinase activity BRAF mutants
- Signaling by high-kinase activity BRAF mutants
- Signaling by BRAF and RAF1 fusions
- Paradoxical activation of RAF signaling by kinase inactive BRAF
- Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
- Regulation of localization of FOXO transcription factors
- Signaling downstream of RAS mutants
- Signaling by RAF1 mutants
- SHOC2 M1731 mutant abolishes MRAS complex function
- Gain-of-function MRAS complexes activate RAF signaling
- SARS-CoV-1 targets host intracellular signalling and regulatory pathways
- SARS-CoV-2 targets host intracellular signalling and regulatory pathways
- Transcriptional and post-translational regulation of MITF-M expression and activity
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- Copper
- Phenethyl Isothiocyanate
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YWHAG
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tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma |
- Activation of BAD and translocation to mitochondria
- Translocation of SLC2A4 (GLUT4) to the plasma membrane
- Regulation of PLK1 Activity at G2/M Transition
- Loss of Nlp from mitotic centrosomes
- Recruitment of mitotic centrosome proteins and complexes
- Loss of proteins required for interphase microtubule organization from the centrosome
- Recruitment of NuMA to mitotic centrosomes
- Anchoring of the basal body to the plasma membrane
- RHO GTPases activate PKNs
- TP53 Regulates Metabolic Genes
- Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
- AURKA Activation by TPX2
- Regulation of localization of FOXO transcription factors
- SARS-CoV-1 targets host intracellular signalling and regulatory pathways
- SARS-CoV-2 targets host intracellular signalling and regulatory pathways
- Transcriptional and post-translational regulation of MITF-M expression and activity
- SPOP-mediated proteasomal degradation of PD-L1(CD274)
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