Search Results for: TLE5

367 interactions involving TLE5 - TLE family member 5, transcriptional modulator found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
EYA2 EYA transcriptional coactivator and phosphatase 2
  • Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
FAM124A family with sequence similarity 124 member A
FAM124B family with sequence similarity 124 member B
FAM168B family with sequence similarity 168 member B
FAM217B family with sequence similarity 217 member B
FAM90A1 family with sequence similarity 90 member A1
FANCG FA complementation group G
  • Fanconi Anemia Pathway
  • PKR-mediated signaling
  • Fanconi anemia
FBF1 Fas binding factor 1
  • Anchoring of the basal body to the plasma membrane
FCHSD2 FCH and double SH3 domains 2
FHL3 four and a half LIM domains 3
FOSB FosB proto-oncogene, AP-1 transcription factor subunit
  • Estrogen-dependent gene expression
  • NGF-stimulated transcription
  • NGF-stimulated transcription
  • Regulation of PD-L1(CD274) transcription
FOXD2 forkhead box D2
FOXN1 forkhead box N1
  • T-B+Severe combined immunodeficiencies (SCIDs), including the following eight diseases: X-linked SCID; Janus kinase-3 (Jak3) deficiency; IL-7 receptor alpha (IL7R alpha) deficiency; IL-2 receptor alpha (IL2R alpha) deficiency; CD45 deficiency; CD3 deficiency; Winged Helix Nude (WHN) deficiency; Immunodeficiency with thynoma
FOXP2 forkhead box P2
  • Positive Regulation of CDH1 Gene Transcription
  • Speech-language disorder 1 (SPCH1)
FRS3 fibroblast growth factor receptor substrate 3
  • FRS-mediated FGFR1 signaling
  • FRS-mediated FGFR2 signaling
  • FRS-mediated FGFR3 signaling
  • FRS-mediated FGFR4 signaling
  • RAF/MAP kinase cascade
  • Activated NTRK2 signals through FRS2 and FRS3
  • RND2 GTPase cycle
  • RND1 GTPase cycle
  • Signaling by ALK fusions and activated point mutants
FSD2 fibronectin type III and SPRY domain containing 2
FXR1 FMR1 autosomal homolog 1
  • Signaling by BRAF and RAF1 fusions
FXR2 FMR1 autosomal homolog 2
GABARAP GABA type A receptor-associated protein
  • Macroautophagy
  • TBC/RABGAPs
GATA1 GATA binding protein 1
  • RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
  • RUNX1 regulates transcription of genes involved in differentiation of HSCs
  • Factors involved in megakaryocyte development and platelet production
  • Congenital dyserythropoietic anemias (CDAs)
  • Thrombocytopenia (THC); Familial platelet disorder with associated myeloid malignancy (FPDMM)

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