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TSPAN7 |
tetraspanin 7 |
- Cell surface interactions at the vascular wall
- Trafficking of GluR2-containing AMPA receptors
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- Non-syndromic X-linked mental retardation
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UPF2 |
UPF2 regulator of nonsense mediated mRNA decay |
- Regulation of expression of SLITs and ROBOs
- Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
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VCAM1 |
vascular cell adhesion molecule 1 |
- Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
- Integrin cell surface interactions
- Interleukin-4 and Interleukin-13 signaling
- Interferon gamma signaling
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- Ethanol
- Carvedilol
- Succinobucol
- Clove oil
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VCAN |
versican |
- Glycosaminoglycan-protein linkage region biosynthesis
- CS-GAG biosynthesis
- DS-GAG biosynthesis
- CS/DS degradation
- ECM proteoglycans
- Defective B4GALT7 causes EDS, progeroid type
- Defective B3GAT3 causes JDSSDHD
- Defective CHST3 causes SEDCJD
- Defective CHST14 causes EDS, musculocontractural type
- Defective CHSY1 causes TPBS
- Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
- Defective B3GALT6 causes EDSP2 and SEMDJL1
- Post-translational protein phosphorylation
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- Vitreoretinal degeneration, including: Stickler syndrome type I (STL1); Stickler syndrome type II (STL2); Snowflake vitreoretinal degeneration (SVD); Wagner syndrome 1 (WGN1); Knobloch syndrome (KNO); Enhanced S-cone syndrome (ESCS); Autosomal dominant vitreoretinochoroidopathy (ADVIRC)
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YWHAB |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta |
- Activation of BAD and translocation to mitochondria
- Translocation of SLC2A4 (GLUT4) to the plasma membrane
- MTOR signalling
- mTORC1-mediated signalling
- Frs2-mediated activation
- Frs2-mediated activation
- ARMS-mediated activation
- Signaling by Hippo
- Rap1 signalling
- Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
- Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA
- RHO GTPases activate PKNs
- TP53 Regulates Metabolic Genes
- RAF activation
- MAP2K and MAPK activation
- Negative regulation of MAPK pathway
- Signaling by moderate kinase activity BRAF mutants
- Signaling by high-kinase activity BRAF mutants
- Signaling by BRAF and RAF1 fusions
- Paradoxical activation of RAF signaling by kinase inactive BRAF
- Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
- Regulation of localization of FOXO transcription factors
- Signaling downstream of RAS mutants
- Signaling by RAF1 mutants
- SHOC2 M1731 mutant abolishes MRAS complex function
- Gain-of-function MRAS complexes activate RAF signaling
- SARS-CoV-1 targets host intracellular signalling and regulatory pathways
- SARS-CoV-2 targets host intracellular signalling and regulatory pathways
- Transcriptional and post-translational regulation of MITF-M expression and activity
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- Copper
- Phenethyl Isothiocyanate
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