Search Results for: brca1

323 interactions involving BRCA1 - BRCA1 DNA repair associated found:

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CSNK1D casein kinase 1 delta
  • COPII-mediated vesicle transport
  • Regulation of PLK1 Activity at G2/M Transition
  • Loss of Nlp from mitotic centrosomes
  • Recruitment of mitotic centrosome proteins and complexes
  • Loss of proteins required for interphase microtubule organization from the centrosome
  • Recruitment of NuMA to mitotic centrosomes
  • Anchoring of the basal body to the plasma membrane
  • Major pathway of rRNA processing in the nucleolus and cytosol
  • AURKA Activation by TPX2
  • The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex
  • Phosphorylation and nuclear translocation of the CRY:PER:kinase complex
CSNK2A1 casein kinase 2 alpha 1
  • Synthesis of PC
  • WNT mediated activation of DVL
  • Condensation of Prometaphase Chromosomes
  • Signal transduction by L1
  • Regulation of TP53 Activity through Phosphorylation
  • Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
  • Receptor Mediated Mitophagy
  • RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
  • Regulation of PTEN stability and activity
  • KEAP1-NFE2L2 pathway
  • Regulation of CDH1 posttranslational processing and trafficking to plasma membrane
  • Maturation of hRSV A proteins
  • SPOP-mediated proteasomal degradation of PD-L1(CD274)
  • Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK
  • Phosphorylation and nuclear translocation of the CRY:PER:kinase complex
  • ATP
  • (5-hydroxyindolo[1,2-a]quinazolin-7-yl)acetic acid
  • 1,8-Di-Hydroxy-4-Nitro-Xanthen-9-One
  • Resveratrol
  • 1,8-Di-Hydroxy-4-Nitro-Anthraquinone
  • Benzamidine
  • 5,8-Di-Amino-1,4-Dihydroxy-Anthraquinone
  • Quercetin
  • Phosphoaminophosphonic Acid-Adenylate Ester
  • Tetrabromo-2-Benzotriazole
  • DIMETHYL-(4,5,6,7-TETRABROMO-1H-BENZOIMIDAZOL-2-YL)-AMINE
  • S-METHYL-4,5,6,7-TETRABROMO-BENZIMIDAZOLE
  • N1,N2-ETHYLENE-2-METHYLAMINO-4,5,6,7-TETRABROMO-BENZIMIDAZOLE
  • Emodin
  • 3,8-DIBROMO-7-HYDROXY-4-METHYL-2H-CHROMEN-2-ONE
  • 19-(cyclopropylamino)-4,6,7,15-tetrahydro-5H-16,1-(azenometheno)-10,14-(metheno)pyrazolo[4,3-o][1,3,9]triazacyclohexadecin-8(9H)-one
  • N,N'-DIPHENYLPYRAZOLO[1,5-A][1,3,5]TRIAZINE-2,4-DIAMINE
  • 4-(2-(1H-IMIDAZOL-4-YL)ETHYLAMINO)-2-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE
  • 2-(CYCLOHEXYLMETHYLAMINO)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE
  • 2-(4-CHLOROBENZYLAMINO)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE
  • 2-(4-ETHYLPIPERAZIN-1-YL)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE
  • N-(3-(8-CYANO-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZIN-2-YLAMINO)PHENYL)ACETAMIDE
  • Dichlororibofuranosylbenzimidazole
  • Quinalizarin
  • Ellagic acid
  • Fostamatinib
CSNK2B casein kinase 2 beta
  • Synthesis of PC
  • WNT mediated activation of DVL
  • Condensation of Prometaphase Chromosomes
  • Signal transduction by L1
  • Neutrophil degranulation
  • Regulation of TP53 Activity through Phosphorylation
  • Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
  • Receptor Mediated Mitophagy
  • RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
  • Regulation of PTEN stability and activity
  • KEAP1-NFE2L2 pathway
  • Regulation of CDH1 posttranslational processing and trafficking to plasma membrane
  • Maturation of hRSV A proteins
  • SPOP-mediated proteasomal degradation of PD-L1(CD274)
  • Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK
  • Phosphorylation and nuclear translocation of the CRY:PER:kinase complex
  • ATP
  • Quercetin
CSTF1 cleavage stimulation factor subunit 1
  • mRNA 3'-end processing
  • Processing of Capped Intron-Containing Pre-mRNA
  • RNA Polymerase II Transcription Termination
  • Processing of Intronless Pre-mRNAs
CTBP1 C-terminal binding protein 1
  • Deactivation of the beta-catenin transactivating complex
  • SUMOylation of transcription cofactors
  • Repression of WNT target genes
  • Signaling by TCF7L2 mutants
  • Negative Regulation of CDH1 Gene Transcription
  • Formic acid
CTCFL CCCTC-binding factor like
CTNNB1 catenin beta 1
  • Degradation of beta-catenin by the destruction complex
  • Beta-catenin phosphorylation cascade
  • TCF dependent signaling in response to WNT
  • Formation of the beta-catenin:TCF transactivating complex
  • Formation of the beta-catenin:TCF transactivating complex
  • LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production
  • Apoptotic cleavage of cell adhesion proteins
  • Deactivation of the beta-catenin transactivating complex
  • Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)
  • Ca2+ pathway
  • Adherens junctions interactions
  • Binding of TCF/LEF:CTNNB1 to target gene promoters
  • Disassembly of the destruction complex and recruitment of AXIN to the membrane
  • Disassembly of the destruction complex and recruitment of AXIN to the membrane
  • VEGFR2 mediated vascular permeability
  • Myogenesis
  • Myogenesis
  • Signaling by GSK3beta mutants
  • CTNNB1 S33 mutants aren't phosphorylated
  • CTNNB1 S37 mutants aren't phosphorylated
  • CTNNB1 S45 mutants aren't phosphorylated
  • CTNNB1 T41 mutants aren't phosphorylated
  • RHO GTPases activate IQGAPs
  • Transcriptional Regulation by VENTX
  • InlA-mediated entry of Listeria monocytogenes into host cells
  • RUNX3 regulates WNT signaling
  • Cardiogenesis
  • Germ layer formation at gastrulation
  • Regulation of CDH11 function
  • Regulation of CDH11 function
  • Regulation of CDH19 Expression and Function
  • Regulation of CDH1 Function
  • Degradation of CDH1
  • Regulation of CDH1 posttranslational processing and trafficking to plasma membrane
  • Formation of paraxial mesoderm
  • Formation of axial mesoderm
  • Formation of definitive endoderm
  • Somitogenesis
  • Regulation of MITF-M-dependent genes involved in pigmentation
  • Regulation of MITF-M-dependent genes involved in cell cycle and proliferation
  • Formation of the nephric duct
  • CDH11 homotypic and heterotypic interactions
  • Specification of the neural plate border
  • High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells
  • Transcriptional and post-translational regulation of MITF-M expression and activity
  • Regulation of PD-L1(CD274) transcription
  • Urea
  • Pilomatricoma; Epithelioma calcificans of Malherbe
  • Gastric cancer
  • Hepatocellular carcinoma
  • Thyroid cancer
  • Colorectal cancer
  • Endometrial Cancer
CUBN cubilin
  • Vitamin D (calciferol) metabolism
  • Defective AMN causes MGA1
  • Defective CUBN causes MGA1
  • HDL clearance
  • Uptake of dietary cobalamins into enterocytes
  • Hydroxocobalamin
CWF19L2 CWF19 like cell cycle control factor 2
  • mRNA Splicing - Major Pathway
DALRD3 DALR anticodon binding domain containing 3
DBF4 DBF4-CDC7 kinase regulatory subunit
  • Activation of ATR in response to replication stress
  • Activation of the pre-replicative complex
DCLRE1C DNA cross-link repair 1C
  • Nonhomologous End-Joining (NHEJ)
  • T-B-Severe combined immunodeficiencies (SCIDs), including the following four diseases: Adenosine deaminase (ADA) deficiency; Recombinase activating gene (RAG) deficiencies; Artemis deficiency; Reticular dysgenesis
DCN decorin
  • Degradation of the extracellular matrix
  • Glycosaminoglycan-protein linkage region biosynthesis
  • CS-GAG biosynthesis
  • DS-GAG biosynthesis
  • CS/DS degradation
  • ECM proteoglycans
  • ECM proteoglycans
  • Defective B4GALT7 causes EDS, progeroid type
  • Defective B3GAT3 causes JDSSDHD
  • Defective CHST3 causes SEDCJD
  • Defective CHST14 causes EDS, musculocontractural type
  • Defective CHSY1 causes TPBS
  • Defective B3GALT6 causes EDSP2 and SEMDJL1
  • Congenital stromal corneal dystrophy (CSCD); Congenital hereditary stromal dystrophy; Witschel dystrophy
DDX24 DEAD-box helicase 24
DES desmin
  • Striated Muscle Contraction
  • Myofibrillar myopathies (MFM), including: Desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Myotilinopathy (MFM3); Zaspopathy (MFM4); Filaminopathy (MFM5); Bag3opathy
  • Dilated cardiomyopathy (DCM)
  • Distal muscular dystrophies, including: Welander distal myopathy (WDM); Tibial muscular dystrophy (TMD); Nonaka distal myopathy with rimmed vacuoles (DMRV); Miyoshi myopathy (MM); Laing myopathy (MPD1); Distal nebulin myopathy (DNM); Distal desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Distal myotilinopathy (MFM3); Distal zaspopathy (MFM4); Distal myopathy 3 (MPD2, VCPDM)
  • Scapuloperoneal myopathy (SPM)
DHPS deoxyhypusine synthase
  • Hypusine synthesis from eIF5A-lysine
  • 1-Guanidinium-7-Aminoheptane
DHX9 DExH-box helicase 9
  • RIP-mediated NFkB activation via ZBP1
  • DEx/H-box helicases activate type I IFN and inflammatory cytokines production
  • mRNA Splicing - Major Pathway
  • PKR-mediated signaling
DNAJA1 DnaJ heat shock protein family (Hsp40) member A1
  • HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
  • Mitochondrial unfolded protein response (UPRmt)
DNAJA3 DnaJ heat shock protein family (Hsp40) member A3
DNAJB1 DnaJ heat shock protein family (Hsp40) member B1
  • Regulation of HSF1-mediated heat shock response
  • HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
  • Attenuation phase
  • HSF1-dependent transactivation
  • MAPK6/MAPK4 signaling

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