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TXNDC11 |
thioredoxin domain containing 11 |
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UBQLN2 |
ubiquilin 2 |
- Cargo recognition for clathrin-mediated endocytosis
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VCP |
valosin containing protein |
- Translesion Synthesis by POLH
- HSF1 activation
- ABC-family proteins mediated transport
- N-glycan trimming in the ER and Calnexin/Calreticulin cycle
- Hedgehog ligand biogenesis
- Hh mutants are degraded by ERAD
- Defective CFTR causes cystic fibrosis
- Josephin domain DUBs
- Ovarian tumor domain proteases
- Neutrophil degranulation
- E3 ubiquitin ligases ubiquitinate target proteins
- Protein methylation
- Neddylation
- RHOH GTPase cycle
- Aggrephagy
- Attachment and Entry
- Attachment and Entry
- KEAP1-NFE2L2 pathway
- AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274)
- Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide
- Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide
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- Phosphoaminophosphonic Acid-Adenylate Ester
- Phenethyl Isothiocyanate
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- Frontotemporal lobar degeneration (FTLD), including: Pick disease of brain; Frontotemporal dementia (FTD); Ubiquitin-positive frontotemporal dementia (UP-FTD); Progressive supranuclear palsy type 1 (PSNP1); Inclusion body myopathy with early-onset paget disease and frontotemporal dementia (IBMPFD); Frontotemporal dementia, chromosome 3-linked (FTD3)
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VWF |
von Willebrand factor |
- Platelet degranulation
- Intrinsic Pathway of Fibrin Clot Formation
- Integrin cell surface interactions
- Integrin signaling
- GRB2:SOS provides linkage to MAPK signaling for Integrins
- p130Cas linkage to MAPK signaling for integrins
- GP1b-IX-V activation signalling
- MAP2K and MAPK activation
- Signaling by moderate kinase activity BRAF mutants
- Signaling by high-kinase activity BRAF mutants
- Signaling by BRAF and RAF1 fusions
- Paradoxical activation of RAF signaling by kinase inactive BRAF
- Platelet Adhesion to exposed collagen
- Platelet Aggregation (Plug Formation)
- Signaling downstream of RAS mutants
- Signaling by RAF1 mutants
- Defective F8 cleavage by thrombin
- Defective F8 binding to von Willebrand factor
- Enhanced cleavage of VWF variant by ADAMTS13
- Enhanced binding of GP1BA variant to VWF multimer:collagen
- Defective VWF cleavage by ADAMTS13 variant
- Defective VWF binding to collagen type I
- Defective binding of VWF variant to GPIb:IX:V
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- Antihemophilic factor, human recombinant
- Egaptivon pegol
- Caplacizumab
- Simoctocog alfa
- Antihemophilic factor (recombinant), PEGylated
- Susoctocog alfa
- Efmoroctocog alfa
- Lonoctocog alfa
- Moroctocog alfa
- Turoctocog alfa pegol
- Rurioctocog alfa pegol
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- Hemophilia; Hemophilia A (HEMA); Hemophilia B (HEMB); von Willebrand disease (VWD)
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