Search Results for: PLEKHF2

176 interactions involving PLEKHF2 - pleckstrin homology and FYVE domain containing 2 found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
CHIC2 cysteine rich hydrophobic domain 2
COX5B cytochrome c oxidase subunit 5B
  • TP53 Regulates Metabolic Genes
  • Respiratory electron transport
  • Cytoprotection by HMOX1
  • Mitochondrial protein degradation
  • Complex IV assembly
  • Cholic Acid
  • N-Formylmethionine
CRYBA1 crystallin beta A1
DAZAP2 DAZ associated protein 2
DMRT3 doublesex and mab-3 related transcription factor 3
DNAAF11 dynein axonemal assembly factor 11
DOCK2 dedicator of cytokinesis 2
  • Nef and signal transduction
  • Neutrophil degranulation
  • RHOA GTPase cycle
  • RAC1 GTPase cycle
  • RAC2 GTPase cycle
  • RHOG GTPase cycle
  • Factors involved in megakaryocyte development and platelet production
DOCK3 dedicator of cytokinesis 3
  • RAC1 GTPase cycle
  • RAC2 GTPase cycle
  • RHOG GTPase cycle
  • NTRK2 activates RAC1
  • NTRK2 activates RAC1
  • Factors involved in megakaryocyte development and platelet production
DPPA4 developmental pluripotency associated 4
  • POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation
  • Zygotic genome activation (ZGA)
DRAP1 DR1 associated protein 1
  • Signaling by NODAL
  • Signaling by Activin
DTX2 deltex E3 ubiquitin ligase 2
  • Activated NOTCH1 Transmits Signal to the Nucleus
  • Activated NOTCH1 Transmits Signal to the Nucleus
DUSP4 dual specificity phosphatase 4
  • RAF-independent MAPK1/3 activation
  • ERKs are inactivated
  • Negative regulation of MAPK pathway
DUT deoxyuridine triphosphatase
  • Deoxyuridine-5'-Diphosphate
  • 1-{(2S,5S)-4-FLUORO-5-[(TRITYLOXY)METHYL]TETRAHYDROFURAN-2-YL}PYRIMIDINE-2,4(1H,3H)-DIONE
EIF3C eukaryotic translation initiation factor 3 subunit C
  • L13a-mediated translational silencing of Ceruloplasmin expression
  • Translation initiation complex formation
  • Formation of a pool of free 40S subunits
  • Formation of the ternary complex, and subsequently, the 43S complex
  • Ribosomal scanning and start codon recognition
  • GTP hydrolysis and joining of the 60S ribosomal subunit
EML2 EMAP like 2
EXOC7 exocyst complex component 7
  • Translocation of SLC2A4 (GLUT4) to the plasma membrane
  • Insulin processing
  • VxPx cargo-targeting to cilium
FAH fumarylacetoacetate hydrolase
  • Tyrosine catabolism
  • Fumaric acid
  • Acetoacetic acid
  • 4-[Hydroxy-[Methyl-Phosphinoyl]]-3-Oxo-Butanoic Acid
  • Tyrosinemia; Tyrosinemia, type I; Tyrosinemia, type II; Tyrosinemia, type III; Hawkinsinuria
FBXO28 F-box protein 28
FBXW5 F-box and WD repeat domain containing 5
  • Association of TriC/CCT with target proteins during biosynthesis
  • Neddylation
  • Antigen processing: Ubiquitination & Proteasome degradation
FGF13 fibroblast growth factor 13
  • Phase 0 - rapid depolarisation

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