NIF3L1 - New-wiki

Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
GNMT	glycine N-methyltransferase	Metabolism of ingested SeMet, Sec, MeSec into H2Se Glyoxylate metabolism and glycine degradation Developmental Lineage of Pancreatic Acinar Cells	Ademetionine Glycine S-adenosyl-L-homocysteine	Hypermethioninemia; Methionine adenosyltransferase deficiency; S-adenosylhomocysteine hydrolase deficiency
GRB2	growth factor receptor bound protein 2	Interleukin-15 signaling Interleukin-15 signaling Signaling by CSF3 (G-CSF) Signaling by CSF3 (G-CSF) STAT5 activation downstream of FLT3 ITD mutants Signaling by FLT3 ITD and TKD mutants Signaling by FLT3 ITD and TKD mutants Signaling by ALK fusions and activated point mutants Signaling by LTK	Pegademase 4-[(10s,14s,18s)-18-(2-Amino-2-Oxoethyl)-14-(1-Naphthylmethyl)-8,17,20-Trioxo-7,16,19-Triazaspiro[5.14]Icos-11-En-10-Yl]Benzylphosphonic Acid
IP6K3	inositol hexakisphosphate kinase 3	Synthesis of pyrophosphates in the cytosol
KCNIP1	potassium voltage-gated channel interacting protein 1	Phase 1 - inactivation of fast Na+ channels
KCTD17	potassium channel tetramerization domain containing 17
KCTD7	potassium channel tetramerization domain containing 7	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
KCTD9	potassium channel tetramerization domain containing 9
KRT15	keratin 15	Keratinization Formation of the cornified envelope Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
KXD1	KxDL motif containing 1
LAMTOR3	late endosomal/lysosomal adaptor, MAPK and MTOR activator 3	Macroautophagy MTOR signalling mTORC1-mediated signalling Energy dependent regulation of mTOR by LKB1-AMPK TP53 Regulates Metabolic Genes MAP2K and MAPK activation Neutrophil degranulation Regulation of PTEN gene transcription Amino acids regulate mTORC1
LMO2	LIM domain only 2	RUNX1 regulates transcription of genes involved in differentiation of HSCs		Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia)
LMO3	LIM domain only 3
MAGEA11	MAGE family member A11
MAPRE2	microtubule associated protein RP/EB family member 2
MLXIPL	MLX interacting protein like	PKA-mediated phosphorylation of key metabolic factors PKA-mediated phosphorylation of key metabolic factors AMPK inhibits chREBP transcriptional activation activity ChREBP activates metabolic gene expression ChREBP activates metabolic gene expression PP2A-mediated dephosphorylation of key metabolic factors
NATD1	N-acetyltransferase domain containing 1
NEK6	NIMA related kinase 6	Activation of NIMA Kinases NEK9, NEK6, NEK7 Nuclear Pore Complex (NPC) Disassembly EML4 and NUDC in mitotic spindle formation
NGB	neuroglobin	Intracellular oxygen transport
NME1	NME/NM23 nucleoside diphosphate kinase 1	Interconversion of nucleotide di- and triphosphates Azathioprine ADME Ribavirin ADME	Zinc 2'-Deoxyguanosine-5'-Triphosphate Selenocysteine 2',3'-Dehydro-2',3'-Deoxy-Thymidine 5'-Diphosphate Adenosine Phosphonoacetic Acid Stavudine triphosphate Thymidine-5'- Diphosphate 2'-Deoxyguanosine-5'-Diphosphate 2',3'-dideoxy-3'-fluoro-urididine-5'-diphosphate Guanosine-5'-Diphosphate 3'-Deoxy 3'-Amino Adenosine-5'-Diphosphate Zidovudine diphosphate Copper Zinc acetate Zinc chloride Zinc sulfate, unspecified form
NME7	NME/NM23 family member 7	Recruitment of mitotic centrosome proteins and complexes Recruitment of NuMA to mitotic centrosomes

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