Search Results for: MIPOL1

76 interactions involving MIPOL1 - mirror-image polydactyly 1 found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
MOS MOS proto-oncogene, serine/threonine kinase
MYLIP myosin regulatory light chain interacting protein
  • VLDLR internalisation and degradation
  • NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake
  • Antigen processing: Ubiquitination & Proteasome degradation
NEBL nebulette
NTAQ1 N-terminal glutamine amidase 1
PAX6 paired box 6
  • Regulation of gene expression in beta cells
  • Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)
  • Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
  • Activation of anterior HOX genes in hindbrain development during early embryogenesis
  • Formation of the anterior neural plate
  • Ocular coloboma, including: Coloboma of iris choroid and retina (COI); Coloboma of optic nerve (COLON)
  • Aniridia
  • Polymicrogyria; Bilateral frontal polymicrogyria (BFP); Bilateral frontoparietal polymicrogyria (BFPP); Bilateral perisylvian polymicrogyria (BPP); Bilateral parasagittal parieto-occipital polymicrogyria (BPOP); Bilateral generalised polymicrogyria (BGP); Unilateral Polymicrogyria (ULP)
PBX4 PBX homeobox 4
PKN1 protein kinase N1
  • RHO GTPases activate PKNs
  • Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
  • RHOA GTPase cycle
  • RHOB GTPase cycle
  • RHOC GTPase cycle
  • RAC1 GTPase cycle
  • Fostamatinib
PPP1R13B protein phosphatase 1 regulatory subunit 13B
  • Activation of PUMA and translocation to mitochondria
  • TP53 Regulates Transcription of Genes Involved in Cytochrome C Release
  • TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain
  • TP53 Regulates Transcription of Death Receptors and Ligands
  • Regulation of TP53 Activity through Association with Co-factors
PRDM16 PR/SET domain 16
  • PKMTs methylate histone lysines
  • Transcriptional regulation of brown and beige adipocyte differentiation by EBF2
PRPF31 pre-mRNA processing factor 31
  • mRNA Splicing - Major Pathway
  • Retinitis pigmentosa (RP)
RBM41 RNA binding motif protein 41
RCOR3 REST corepressor 3
REL REL proto-oncogene, NF-kB subunit
  • Activation of NF-kappaB in B cells
  • Hodgkin lymphoma
RIIAD1 regulatory subunit of type II PKA R-subunit domain containing 1
RNF6 ring finger protein 6
  • Antigen processing: Ubiquitination & Proteasome degradation
RTP5 receptor transporter protein 5 (putative)
SCNM1 sodium channel modifier 1
SHANK3 SH3 and multiple ankyrin repeat domains 3
  • Neurexins and neuroligins
  • Neurexins and neuroligins
  • RET signaling
SMARCE1 SWI/SNF related BAF chromatin remodeling complex subunit E1
  • RMTs methylate histone arginines
  • RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
  • Regulation of MITF-M-dependent genes involved in pigmentation
  • Regulation of MITF-M-dependent genes involved in pigmentation
  • Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs)
  • Formation of the canonical BAF (cBAF) complex
  • Formation of the polybromo-BAF (pBAF) complex
  • Formation of the embryonic stem cell BAF (esBAF) complex
  • Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)
  • Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)
  • Phenethyl Isothiocyanate
SNAP91 synaptosome associated protein 91
  • Cargo recognition for clathrin-mediated endocytosis
  • Clathrin-mediated endocytosis

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