Search Results for: IKZF3

166 interactions involving IKZF3 - IKAROS family zinc finger 3 found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Symbol Description Pathways Hide Drugs Hide Diseases Hide
CDKN2D cyclin dependent kinase inhibitor 2D
  • Oxidative Stress Induced Senescence
  • Senescence-Associated Secretory Phenotype (SASP)
  • Oncogene Induced Senescence
  • Cyclin D associated events in G1
CFAP206 cilia and flagella associated protein 206
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2
  • Mitochondrial protein import
  • Mitochondrial protein degradation
CHD3 chromodomain helicase DNA binding protein 3
  • HDACs deacetylate histones
  • ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
  • SUMOylation of chromatin organization proteins
  • Regulation of TP53 Activity through Acetylation
  • RNA Polymerase I Transcription Initiation
  • Regulation of PTEN gene transcription
  • Regulation of PTEN gene transcription
  • Potential therapeutics for SARS
  • Regulation of endogenous retroelements by KRAB-ZFP proteins
  • Transcriptional regulation of brown and beige adipocyte differentiation by EBF2
  • Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs)
CKS1B CDC28 protein kinase regulatory subunit 1B
  • SCF(Skp2)-mediated degradation of p27/p21
  • Cyclin D associated events in G1
  • Fluoxetine
  • 2,8-bis[oxido(oxo)vanadio]-1,1,1,3,5,5,7,7,9,9,9-undecaoxopentavanadoxane-2,8-diium
CLCNKA chloride voltage-gated channel Ka
  • Stimuli-sensing channels
  • Niflumic acid
  • Talniflumate
  • Bartter syndrome
CRBN cereblon
  • Potential therapeutics for SARS
  • Lenalidomide
  • Thalidomide
  • Pomalidomide
  • Nonsyndromic autosomal recessive mental retardation (NS-ARMR)
CRK CRK proto-oncogene, adaptor protein
  • ARMS-mediated activation
  • ARMS-mediated activation
  • Downstream signal transduction
  • Regulation of actin dynamics for phagocytic cup formation
  • p130Cas linkage to MAPK signaling for integrins
  • VEGFA-VEGFR2 Pathway
  • PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
  • MET activates RAP1 and RAC1
  • MET receptor recycling
  • Regulation of signaling by CBL
  • FCGR3A-mediated phagocytosis
CRYBA4 crystallin beta A4
  • Anophthalmia and microphthalmia (A/M)
DGCR6 DiGeorge syndrome critical region gene 6
DTX2 deltex E3 ubiquitin ligase 2
  • Activated NOTCH1 Transmits Signal to the Nucleus
  • Activated NOTCH1 Transmits Signal to the Nucleus
EFHC1 EF-hand domain containing 1
  • Idiopathic generalied epilepsies (IGEs), including: Childhood absence epilepsy (CAE); Juvenile absence epilepsy (JAE); Juvenile myoclonic epilepsy (JME); Epilepsy with generalized tonic-clonic seizures alone
EGLN3 egl-9 family hypoxia inducible factor 3
  • Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
  • Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
  • Ascorbic acid
  • Roxadustat
  • Daprodustat
  • Vadadustat
EMC2 ER membrane protein complex subunit 2
ENKD1 enkurin domain containing 1
EXOC8 exocyst complex component 8
  • Translocation of SLC2A4 (GLUT4) to the plasma membrane
  • Insulin processing
  • VxPx cargo-targeting to cilium
EXOSC5 exosome component 5
  • ATF4 activates genes in response to endoplasmic reticulum stress
  • mRNA decay by 3' to 5' exoribonuclease
  • Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
  • Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA
  • KSRP (KHSRP) binds and destabilizes mRNA
  • Major pathway of rRNA processing in the nucleolus and cytosol
  • Nuclear RNA decay
FAM124B family with sequence similarity 124 member B
FANCG FA complementation group G
  • Fanconi Anemia Pathway
  • PKR-mediated signaling
  • Fanconi anemia
FANCL FA complementation group L
  • Fanconi Anemia Pathway
  • PKR-mediated signaling
  • Fanconi anemia

Page 3 out of 9 pages