Search Results for: ERBB3

203 interactions involving ERBB3 - erb-b2 receptor tyrosine kinase 3 found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Symbol Description Pathways Hide Drugs Hide Diseases Hide
ERBB4 erb-b2 receptor tyrosine kinase 4
  • Afatinib
  • Fostamatinib
  • Brigatinib
  • Zanubrutinib
ERG28 ergosterol biosynthesis 28 homolog
EYA4 EYA transcriptional coactivator and phosphatase 4
  • Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
EZR ezrin
  • Netrin-1 signaling
  • Recycling pathway of L1
  • Recycling pathway of L1
  • Sensory processing of sound by inner hair cells of the cochlea
  • Sensory processing of sound by outer hair cells of the cochlea
FAM241B family with sequence similarity 241 member B
FER FER tyrosine kinase
  • Signaling by SCF-KIT
  • Fostamatinib
FES FES proto-oncogene, tyrosine kinase
  • Signaling by SCF-KIT
  • Sema3A PAK dependent Axon repulsion
  • SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
  • CRMPs in Sema3A signaling
  • Fostamatinib
FGFR1 fibroblast growth factor receptor 1
  • Signaling by activated point mutants of FGFR1
  • Signaling by FGFR1 in disease
  • Signaling by plasma membrane FGFR1 fusions
  • Epithelial-Mesenchymal Transition (EMT) during gastrulation
  • Formation of paraxial mesoderm
  • Palifermin
  • Sorafenib
  • Heparin
  • 3-[4-(1-formylpiperazin-4-yl)-benzylidenyl]-2-indolinone
  • XL999
  • 3-(3-methoxybenzyl)-1H-pyrrolo[2,3-b]pyridine
  • (E)-[4-(3,5-Difluorophenyl)-3H-pyrrolo[2,3-b]pyridin-3-ylidene](3-methoxyphenyl)methanol
  • 3-[(3-(2-CARBOXYETHYL)-4-METHYLPYRROL-2-YL)METHYLENE]-2-INDOLINONE
  • Regorafenib
  • Ponatinib
  • Lenvatinib
  • Nintedanib
  • Tivozanib
  • Infigratinib
  • Fostamatinib
  • Erdafitinib
  • Pemigatinib
  • Futibatinib
  • Selpercatinib
  • Pralsetinib
  • Hypogonadotropic hypogonadism; Kallmann syndrome (KAL)
  • Craniosynostosis, including: Pfeiffer syndrome; Apert syndrome; Crouzon syndrome; Jackson-Weiss syndrome; Beare-Stevenson syndrome; Muenke craniosynostosis; Saethre-Chotzen syndrome; Craniosynostosis Boston type; Antley-Bixler syndrome; Carpenter syndrome; Craniofrontonasal dysplasia; Noonan syndrome; Baller-Gerold syndrome
  • Osteoglophonic dysplasia (OD); Osteoglophonic dwarfism (OGD)
  • Isolated orofacial clefts, including: Cleft lip with or without cleft palate; Cleft palate
FGR FGR proto-oncogene, Src family tyrosine kinase
  • FCGR activation
  • Platelet sensitization by LDL
  • Neutrophil degranulation
  • FCGR3A-mediated IL10 synthesis
  • FCGR3A-mediated phagocytosis
  • Dasatinib
  • Fostamatinib
  • Zanubrutinib
FHL3 four and a half LIM domains 3
FKBP1A FKBP prolyl isomerase 1A
  • mTORC1-mediated signalling
  • Calcineurin activates NFAT
  • Calcineurin activates NFAT
  • TGF-beta receptor signaling activates SMADs
  • TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
  • TGFBR1 LBD Mutants in Cancer
  • Potential therapeutics for SARS
  • SARS-CoV-1 activates/modulates innate immune responses
  • Pimecrolimus
  • Tacrolimus
  • (3R)-4-(p-toluenesulfonyl)-1,4-thiazane-3-carboxylicacid-L-phenylalanine ethyl ester
  • {3-[3-(3,4-Dimethoxy-Phenyl)-1-(1-{1-[2-(3,4,5-Trimethoxy-Phenyl)-Butyryl]-Piperidin-2yl}-Vinyloxy)-Propyl]-Phenoxy}-Acetic Acid
  • Gpi-1046
  • Methyl Methylsulfinylmethyl Sulfide
  • FKB-001
  • Heptyl glucoside
  • L-709,587
  • (3r)-4-(P-Toluenesulfonyl)-1,4-Thiazane-3-Carboxylicacid-L-Leucine
  • 4-hydroxybutan-2-one
  • GPI-1485
  • Myristic acid
  • (21S)-1AZA-4,4-DIMETHYL-6,19-DIOXA-2,3,7,20-TETRAOXOBICYCLO[19.4.0] PENTACOSANE
  • Dorsomorphin
FLNA filamin A
  • Platelet degranulation
  • GP1b-IX-V activation signalling
  • Cell-extracellular matrix interactions
  • RHO GTPases activate PAKs
  • OAS antiviral response
  • Artenimol
  • FG syndrome (FGS); Opitz-Kaveggia syndrome
  • Periventricular nodular heterotopia (PVNH)
  • Syndromic X-linked mental retardation with epilepsy or seizures, including: West syndrome (WS); Partington syndrome (PRTS); Proud syndrome (ACCAG); XMR and epilepsy (XMRE); MRXHF1; XMR OPHN1-related (MRXSO) ; XELBD; XMR, Christianson type (MRXSC); Creatine deficiency syndrome (XL-CDS); Renpenning syndrome (RENS1); Epilepsy and mental retardation limited to females (EFMR); Periventricular nodular heterotopia (PVNH); Hydrocephalus (XLH); XMR, JARID1C related (MRXSJ); Boerjeson-Forssman syndrome (BFLS); CK syndrome (CKS)
  • Fronto-Otopalatodigital Osteodysplasia, including: Otopalatodigital syndrome, type I; Otopalatodigital syndrome, type II; Melnick-Needles syndrome; Frontometaphyseal dysplasia
FLYWCH1 FLYWCH-type zinc finger 1
GABARAPL1 GABA type A receptor associated protein like 1
  • Macroautophagy
GABARAPL2 GABA type A receptor associated protein like 2
  • Macroautophagy
  • TBC/RABGAPs
GRAP2 GRB2 related adaptor protein 2
  • Signaling by SCF-KIT
  • Generation of second messenger molecules
  • DAP12 signaling
  • FCERI mediated MAPK activation
  • FCERI mediated Ca+2 mobilization
  • FCERI mediated Ca+2 mobilization
  • Co-stimulation by CD28
  • FLT3 Signaling
  • Signaling by CSF1 (M-CSF) in myeloid cells
GRB2 growth factor receptor bound protein 2
  • Interleukin-15 signaling
  • Interleukin-15 signaling
  • Signaling by CSF3 (G-CSF)
  • Signaling by CSF3 (G-CSF)
  • STAT5 activation downstream of FLT3 ITD mutants
  • Signaling by FLT3 ITD and TKD mutants
  • Signaling by FLT3 ITD and TKD mutants
  • Signaling by ALK fusions and activated point mutants
  • Signaling by LTK
  • Pegademase
  • 4-[(10s,14s,18s)-18-(2-Amino-2-Oxoethyl)-14-(1-Naphthylmethyl)-8,17,20-Trioxo-7,16,19-Triazaspiro[5.14]Icos-11-En-10-Yl]Benzylphosphonic Acid
GRB7 growth factor receptor bound protein 7
  • GRB7 events in ERBB2 signaling
  • Signaling by SCF-KIT
  • Downstream signal transduction
  • Tie2 Signaling
  • RET signaling
  • RND1 GTPase cycle
HCK HCK proto-oncogene, Src family tyrosine kinase
  • Nef and signal transduction
  • FCGR activation
  • Regulation of signaling by CBL
  • Regulation of signaling by CBL
  • FCGR3A-mediated IL10 synthesis
  • FCGR3A-mediated phagocytosis
  • Signaling by CSF3 (G-CSF)
  • Signaling by CSF3 (G-CSF)
  • Signaling by CSF1 (M-CSF) in myeloid cells
  • Inactivation of CSF3 (G-CSF) signaling
  • Inactivation of CSF3 (G-CSF) signaling
  • FLT3 signaling through SRC family kinases
  • 1-Ter-Butyl-3-P-Tolyl-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine
  • Phosphonotyrosine
  • Quercetin
  • Bosutinib
  • Fostamatinib
HDAC6 histone deacetylase 6
  • NOTCH1 Intracellular Domain Regulates Transcription
  • Constitutive Signaling by NOTCH1 PEST Domain Mutants
  • Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
  • HSF1 activation
  • Notch-HLH transcription pathway
  • Cargo trafficking to the periciliary membrane
  • Transcriptional regulation by RUNX2
  • RUNX2 regulates osteoblast differentiation
  • Chaperone Mediated Autophagy
  • Late endosomal microautophagy
  • Aggrephagy
  • Aggrephagy
  • Valproic acid
  • Decitabine
  • Vorinostat
  • Vorinostat
  • Belinostat
  • Pracinostat
  • Romidepsin
  • Romidepsin
  • Panobinostat
  • Phenylbutyric acid
  • Entinostat
  • Abexinostat
  • Givinostat
  • Pyroxamide
  • Bufexamac

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