ARL13B - New-wiki

Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
EMP1	epithelial membrane protein 1
ENTPD3	ectonucleoside triphosphate diphosphohydrolase 3	Phosphate bond hydrolysis by NTPDase proteins
ERG28	ergosterol biosynthesis 28 homolog
FAXDC2	fatty acid hydroxylase domain containing 2
FDFT1	farnesyl-diphosphate farnesyltransferase 1	Cholesterol biosynthesis PPARA activates gene expression Activation of gene expression by SREBF (SREBP)	TAK-475
FKBP8	FKBP prolyl isomerase 8	Ub-specific processing proteases
FUNDC2	FUN14 domain containing 2
FXYD6	FXYD domain containing ion transport regulator 6	Ion homeostasis Ion transport by P-type ATPases Potential therapeutics for SARS
GAD2	glutamate decarboxylase 2	GABA synthesis GABA synthesis, release, reuptake and degradation MECP2 regulates transcription of genes involved in GABA signaling	Pyridoxal phosphate Glutamic acid
GIMAP1	GTPase, IMAP family member 1
GIMAP5	GTPase, IMAP family member 5
GJB2	gap junction protein beta 2	Oligomerization of connexins into connexons Transport of connexins along the secretory pathway Gap junction assembly Transport of connexons to the plasma membrane		Deafness, autosomal recessive Keratitis-ichthyosis-deafness syndrome Vohwinkel syndrome, including: Vohwinkel syndrome (VS); Vohwinkel syndrome with ichthyosis Deafness, autosomal dominant Palmoplantar keratoderma with deafness
GOSR2	golgi SNAP receptor complex member 2	COPII-mediated vesicle transport XBP1(S) activates chaperone genes Cargo concentration in the ER COPI-mediated anterograde transport Intra-Golgi traffic
GPR37L1	G protein-coupled receptor 37 like 1	Peptide ligand-binding receptors G alpha (i) signalling events
HMOX1	heme oxygenase 1	Heme degradation Interleukin-4 and Interleukin-13 signaling The NLRP3 inflammasome Iron uptake and transport Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Purinergic signaling in leishmaniasis infection Cytoprotection by HMOX1 Cytoprotection by HMOX1 Regulation of HMOX1 expression and activity Heme signaling NFE2L2 regulating anti-oxidant/detoxification enzymes	NADH Formic acid Biliverdine IX Alpha 12-Phenylheme 2-Phenylheme Verdoheme Stannsoporfin 1-({2-[2-(4-CHLOROPHENYL)ETHYL]-1,3-DIOXOLAN-2-YL}METHYL)-1H-IMIDAZOLE 1-(adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanone
HMOX2	heme oxygenase 2	Heme degradation Neutrophil degranulation RHOA GTPase cycle Iron uptake and transport Cytoprotection by HMOX1	NADH Stannsoporfin
HOMER3	homer scaffold protein 3	Neurexins and neuroligins Neurexins and neuroligins
ICMT	isoprenylcysteine carboxyl methyltransferase	Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation RAS processing
IGFBP5	insulin like growth factor binding protein 5	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
INSIG2	insulin induced gene 2	Regulation of cholesterol biosynthesis by SREBP (SREBF)

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