|
|
ANK3 |
ankyrin 3 |
- Interaction between L1 and Ankyrins
- Interaction between L1 and Ankyrins
- COPI-mediated anterograde transport
- Regulation of CDH1 posttranslational processing and trafficking to plasma membrane
|
|
|
|
|
ANKFY1 |
ankyrin repeat and FYVE domain containing 1 |
|
|
|
|
|
ANKRD35 |
ankyrin repeat domain 35 |
|
|
|
|
|
AP1M1 |
adaptor related protein complex 1 subunit mu 1 |
- Nef mediated downregulation of MHC class I complex cell surface expression
- MHC class II antigen presentation
- Lysosome Vesicle Biogenesis
- Golgi Associated Vesicle Biogenesis
- Neutrophil degranulation
|
|
|
|
|
APEX1 |
apurinic/apyrimidinic endodeoxyribonuclease 1 |
- Displacement of DNA glycosylase by APEX1
- POLB-Dependent Long Patch Base Excision Repair
- Resolution of AP sites via the multiple-nucleotide patch replacement pathway
- PCNA-Dependent Long Patch Base Excision Repair
- Abasic sugar-phosphate removal via the single-nucleotide replacement pathway
- Resolution of Abasic Sites (AP sites)
|
|
|
|
|
APOBEC3C |
apolipoprotein B mRNA editing enzyme catalytic subunit 3C |
- mRNA Editing: C to U Conversion
- Formation of the Editosome
|
|
|
|
|
APP |
amyloid beta precursor protein |
- Platelet degranulation
- ECM proteoglycans
- Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
- G alpha (q) signalling events
- G alpha (i) signalling events
- Lysosome Vesicle Biogenesis
- Formyl peptide receptors bind formyl peptides and many other ligands
- TAK1-dependent IKK and NF-kappa-B activation
- The NLRP3 inflammasome
- Advanced glycosylation endproduct receptor signaling
- Advanced glycosylation endproduct receptor signaling
- Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
- Post-translational protein phosphorylation
- TRAF6 mediated NF-kB activation
- Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
- Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
- Purinergic signaling in leishmaniasis infection
- Amyloid fiber formation
|
- Deferoxamine
- Aluminium
- Zinc
- L-methionine (R)-S-oxide
- Resveratrol
- Tromethamine
- Phenserine
- Tetrathiomolybdate
- CAD106
- Mito-4509
- Edonerpic
- Dimercaprol
- Copper
- Florbetaben (18F)
- Florbetapir (18F)
- Flutemetamol (18F)
- Gantenerumab
- Aducanumab
- Zinc acetate
- Aluminium phosphate
- Aluminum acetate
- Zinc chloride
- Zinc sulfate, unspecified form
- Lecanemab
|
|
|
|
ARFGEF3 |
ARFGEF family member 3 |
|
|
|
|
|
ARGLU1 |
arginine and glutamate rich 1 |
|
|
|
|
|
ARHGAP12 |
Rho GTPase activating protein 12 |
- RAC1 GTPase cycle
- RHOD GTPase cycle
- RHOV GTPase cycle
- RHOF GTPase cycle
|
|
|
|
|
ARK2N |
arkadia (RNF111) N-terminal like PKA signaling regulator 2N |
|
|
|
|
|
ARL6IP4 |
ARF like GTPase 6 interacting protein 4 |
|
|
|
|
|
ARPC1B |
actin related protein 2/3 complex subunit 1B |
- Regulation of actin dynamics for phagocytic cup formation
- Regulation of actin dynamics for phagocytic cup formation
- EPHB-mediated forward signaling
- RHO GTPases Activate WASPs and WAVEs
- RHO GTPases Activate WASPs and WAVEs
- FCGR3A-mediated phagocytosis
- FCGR3A-mediated phagocytosis
|
- N-[2-(2-methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamide
- (2S)-2-(3-bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-1,3-thiazolidin-4-one
|
|
|
|
ARSG |
arylsulfatase G |
- The activation of arylsulfatases
- Glycosphingolipid catabolism
|
|
|
|
|
ASL |
argininosuccinate lyase |
|
- Arginine
- Argininosuccinate
- 2-(N-morpholino)ethanesulfonic acid
|
- Argininosuccinic aciduria (ARGINSA); Argininosuccinate lyase deficiency
|
|
|
ATAT1 |
alpha tubulin acetyltransferase 1 |
- Cargo trafficking to the periciliary membrane
|
|
|
|
|
AURKA |
aurora kinase A |
- APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
- Regulation of PLK1 Activity at G2/M Transition
- SUMOylation of DNA replication proteins
- TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
- Regulation of TP53 Activity through Phosphorylation
- FBXL7 down-regulates AURKA during mitotic entry and in early mitosis
- AURKA Activation by TPX2
- Interaction between PHLDA1 and AURKA
|
- Phosphonothreonine
- AT9283
- CYC116
- Alisertib
- SNS-314
- Cenisertib
- Enzastaurin
- 4-(4-METHYLPIPERAZIN-1-YL)-N-[5-(2-THIENYLACETYL)-1,5-DIHYDROPYRROLO[3,4-C]PYRAZOL-3-YL]BENZAMIDE
- AKI-001
- 1-{5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-1,3-thiazol-2-yl}-3-[3-(trifluoromethyl)phenyl]urea
- 1-(5-{2-[(1-methyl-1H-pyrazolo[4,3-d]pyrimidin-7-yl)amino]ethyl}-1,3-thiazol-2-yl)-3-[3-(trifluoromethyl)phenyl]urea
- N-{3-[(4-{[3-(TRIFLUOROMETHYL)PHENYL]AMINO}PYRIMIDIN-2-YL)AMINO]PHENYL}CYCLOPROPANECARBOXAMIDE
- N-butyl-3-{[6-(9H-purin-6-ylamino)hexanoyl]amino}benzamide
- 2-(1H-pyrazol-3-yl)-1H-benzimidazole
- N-[3-(1H-BENZIMIDAZOL-2-YL)-1H-PYRAZOL-4-YL]BENZAMIDE
- Fostamatinib
- MK-5108
- MLN8054
|
|
|
|
BAG3 |
BAG cochaperone 3 |
- Regulation of HSF1-mediated heat shock response
|
|
|
|
|
BAIAP2 |
BAR/IMD domain containing adaptor protein 2 |
- Regulation of actin dynamics for phagocytic cup formation
- Regulation of actin dynamics for phagocytic cup formation
- VEGFA-VEGFR2 Pathway
- RHO GTPases Activate WASPs and WAVEs
- RHO GTPases Activate WASPs and WAVEs
- CDC42 GTPase cycle
- RAC1 GTPase cycle
- RAC3 GTPase cycle
- FCGR3A-mediated phagocytosis
- FCGR3A-mediated phagocytosis
|
|
|
|
|
BAZ1A |
bromodomain adjacent to zinc finger domain 1A |
|
|
|