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ATXN7L2
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ataxin 7 like 2 |
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BCAS2
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BCAS2 pre-mRNA processing factor |
- mRNA Splicing - Major Pathway
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BCL2L1
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BCL2 like 1 |
- BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members
- Interleukin-4 and Interleukin-13 signaling
- The NLRP1 inflammasome
- RAS processing
- SARS-CoV-1-mediated effects on programmed cell death
- STAT5 activation downstream of FLT3 ITD mutants
- NFE2L2 regulating tumorigenic genes
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- 4'-FLUORO-1,1'-BIPHENYL-4-CARBOXYLIC ACID
- Gossypol
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BLK
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BLK proto-oncogene, Src family tyrosine kinase |
- RUNX1 regulates transcription of genes involved in BCR signaling
- Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
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- Fostamatinib
- Zanubrutinib
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- Maturity onset diabetes of the young (MODY)
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BLZF1
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basic leucine zipper nuclear factor 1 |
- Golgi Cisternae Pericentriolar Stack Reorganization
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BYSL
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bystin like |
- Major pathway of rRNA processing in the nucleolus and cytosol
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CABP4
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calcium binding protein 4 |
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- Congenital stationary night blindness (CSNB), including: CSNB type 1 (CSNB1); CSNB type 2 (CSNB2); CSNB autosomal dominant (CSNBAD); Oguchi disease/ CSNB Oguchi type (CSNBO)
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CABP5
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calcium binding protein 5 |
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CARD9
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caspase recruitment domain family member 9 |
- NOD1/2 Signaling Pathway
- CLEC7A (Dectin-1) signaling
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- Chronic Mucocutaneous Candidiasis (CMC); Familial candidiasis (CANDF)
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CATSPER1
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cation channel sperm associated 1 |
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- Bisphenol A diglycidyl ether
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CATSPERT
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catsper channel auxiliary subunit tau |
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CCDC102B
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coiled-coil domain containing 102B |
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CCDC187
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coiled-coil domain containing 187 |
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CCDC24
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coiled-coil domain containing 24 |
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CCDC57
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coiled-coil domain containing 57 |
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CCHCR1
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coiled-coil alpha-helical rod protein 1 |
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CDC37
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cell division cycle 37, HSP90 cochaperone |
- Signaling by ERBB2
- Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants
- Constitutive Signaling by EGFRvIII
- Regulation of necroptotic cell death
- Downregulation of ERBB2 signaling
- RHOBTB2 GTPase cycle
- Constitutive Signaling by Overexpressed ERBB2
- Drug-mediated inhibition of ERBB2 signaling
- Signaling by ERBB2 KD Mutants
- Resistance of ERBB2 KD mutants to trastuzumab
- Resistance of ERBB2 KD mutants to sapitinib
- Resistance of ERBB2 KD mutants to tesevatinib
- Resistance of ERBB2 KD mutants to neratinib
- Resistance of ERBB2 KD mutants to osimertinib
- Resistance of ERBB2 KD mutants to afatinib
- Resistance of ERBB2 KD mutants to AEE788
- Resistance of ERBB2 KD mutants to lapatinib
- Signaling by ERBB2 ECD mutants
- Signaling by ERBB2 TMD/JMD mutants
- Drug resistance in ERBB2 TMD/JMD mutants
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CDC7
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cell division cycle 7 |
- Activation of ATR in response to replication stress
- Activation of the pre-replicative complex
- Transcriptional Regulation by E2F6
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CDK4
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cyclin dependent kinase 4 |
- SCF(Skp2)-mediated degradation of p27/p21
- Oxidative Stress Induced Senescence
- Senescence-Associated Secretory Phenotype (SASP)
- Oncogene Induced Senescence
- RMTs methylate histone arginines
- Transcriptional regulation of white adipocyte differentiation
- Cyclin D associated events in G1
- Ubiquitin-dependent degradation of Cyclin D
- Ubiquitin-dependent degradation of Cyclin D
- PTK6 Regulates Cell Cycle
- Transcriptional regulation by RUNX2
- Meiotic recombination
- Transcriptional regulation of granulopoiesis
- Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4
- Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6
- Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4
- Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6
- Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)
- Drug-mediated inhibition of CDK4/CDK6 activity
- SPOP-mediated proteasomal degradation of PD-L1(CD274)
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- Purvalanol
- Alvocidib
- Palbociclib
- Ribociclib
- Abemaciclib
- Fostamatinib
- Trilaciclib
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- Malignant melanoma
- Glioma
- Cervical cancer
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CDKN1A
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cyclin dependent kinase inhibitor 1A |
- SCF(Skp2)-mediated degradation of p27/p21
- AKT phosphorylates targets in the cytosol
- Senescence-Associated Secretory Phenotype (SASP)
- DNA Damage/Telomere Stress Induced Senescence
- Constitutive Signaling by AKT1 E17K in Cancer
- Interleukin-4 and Interleukin-13 signaling
- TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest
- Cyclin E associated events during G1/S transition
- Cyclin D associated events in G1
- p53-Dependent G1 DNA Damage Response
- Cyclin A:Cdk2-associated events at S phase entry
- Transcriptional activation of cell cycle inhibitor p21
- The role of GTSE1 in G2/M progression after G2 checkpoint
- TFAP2 (AP-2) family regulates transcription of cell cycle factors
- Transcriptional regulation by RUNX2
- RUNX3 regulates CDKN1A transcription
- Neddylation
- Transcriptional regulation of granulopoiesis
- FOXO-mediated transcription of cell cycle genes
- Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)
- STAT5 activation downstream of FLT3 ITD mutants
- Signaling by FLT3 fusion proteins
- Signaling by ALK fusions and activated point mutants
- KEAP1-NFE2L2 pathway
- Regulation of MITF-M-dependent genes involved in cell cycle and proliferation
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- Valproic acid
- Arsenic trioxide
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