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PTEN |
phosphatase and tensin homolog |
- Synthesis of PIPs at the plasma membrane
- Synthesis of IP3 and IP4 in the cytosol
- Negative regulation of the PI3K/AKT network
- Downstream TCR signaling
- TP53 Regulates Metabolic Genes
- PTEN Loss of Function in Cancer
- Ub-specific processing proteases
- Ovarian tumor domain proteases
- Regulation of PTEN mRNA translation
- Regulation of PTEN localization
- Regulation of PTEN stability and activity
- Transcriptional Regulation by MECP2
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- Vulvar cancer
- Breast cancer
- Malignant melanoma
- Prostate cancer
- Hepatocellular carcinoma
- Small cell lung cancer
- Endometrial Cancer
- Glioma
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RBFOX2 |
RNA binding fox-1 homolog 2 |
- FGFR2 alternative splicing
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TP63 |
tumor protein p63 |
- Activation of PUMA and translocation to mitochondria
- Pyroptosis
- TP53 Regulates Metabolic Genes
- TP53 Regulates Transcription of Genes Involved in Cytochrome C Release
- TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain
- TP53 Regulates Transcription of Caspase Activators and Caspases
- TP53 Regulates Transcription of Death Receptors and Ligands
- Regulation of TP53 Activity through Association with Co-factors
- Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
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- Split-hand/foot malformation (SHFM)
- Limb-mammary syndrome
- Ectrodactyly-ectodermal dysplasia cleft-palate syndrome (EEC syndrome)
- ADULT syndrome
- Ankyloblepharon-ctodermal defects-cleft lip/palate (AEC) syndrome and Rapp-Hodgkin syndrome
- Isolated orofacial clefts, including: Cleft lip with or without cleft palate; Cleft palate
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USP19 |
ubiquitin specific peptidase 19 |
- Ub-specific processing proteases
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YWHAG |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma |
- Activation of BAD and translocation to mitochondria
- Translocation of SLC2A4 (GLUT4) to the plasma membrane
- Regulation of PLK1 Activity at G2/M Transition
- Loss of Nlp from mitotic centrosomes
- Recruitment of mitotic centrosome proteins and complexes
- Loss of proteins required for interphase microtubule organization from the centrosome
- Recruitment of NuMA to mitotic centrosomes
- Anchoring of the basal body to the plasma membrane
- RHO GTPases activate PKNs
- TP53 Regulates Metabolic Genes
- Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
- AURKA Activation by TPX2
- Regulation of localization of FOXO transcription factors
- SARS-CoV-1 targets host intracellular signalling and regulatory pathways
- SARS-CoV-2 targets host intracellular signalling and regulatory pathways
- Transcriptional and post-translational regulation of MITF-M expression and activity
- SPOP-mediated proteasomal degradation of PD-L1(CD274)
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