G3BP1 - New-wiki

Interactant Symbol	Name	Associated Pathways Hide
SPOP	speckle type BTB/POZ protein	Hedgehog 'on' state SPOP-mediated proteasomal degradation of PD-L1(CD274)
TRIM21	tripartite motif containing 21	STING mediated induction of host immune responses Regulation of innate immune responses to cytosolic DNA Interferon gamma signaling KEAP1-NFE2L2 pathway Antigen processing: Ubiquitination & Proteasome degradation
TRIM25	tripartite motif containing 25	ISG15 antiviral mechanism DDX58/IFIH1-mediated induction of interferon-alpha/beta Termination of translesion DNA synthesis Ovarian tumor domain proteases Interferon gamma signaling TRAF3-dependent IRF activation pathway TRAF6 mediated IRF7 activation TRAF6 mediated NF-kB activation TRAF6 mediated NF-kB activation NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 Negative regulators of DDX58/IFIH1 signaling Negative regulators of DDX58/IFIH1 signaling SARS-CoV-1 activates/modulates innate immune responses SARS-CoV-2 activates/modulates innate and adaptive immune responses Evasion by RSV of host interferon responses RSV-host interactions PKR-mediated signaling Modulation of host responses by IFN-stimulated genes
UBAP2L	ubiquitin associated protein 2 like
USP10	ubiquitin specific peptidase 10	Termination of translesion DNA synthesis Ub-specific processing proteases
USP13	ubiquitin specific peptidase 13	Ub-specific processing proteases Regulation of PTEN stability and activity
USP2	ubiquitin specific peptidase 2	TNFR1-induced proapoptotic signaling Regulation of TNFR1 signaling TNFR1-induced NF-kappa-B signaling pathway Ub-specific processing proteases Regulation of TP53 Degradation

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