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STX11 |
syntaxin 11 |
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- Familial hemophagocytic lymphohistiocytosis (FHPL), including the following three diseases: Perforin deficiency; Munc deficiency; STX11 deficiency
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SUFU |
SUFU negative regulator of hedgehog signaling |
- Degradation of GLI1 by the proteasome
- Degradation of GLI1 by the proteasome
- Degradation of GLI2 by the proteasome
- GLI3 is processed to GLI3R by the proteasome
- Hedgehog 'off' state
- Hedgehog 'on' state
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- Basal cell nevus syndrome; Nevoid basal cell carcinoma syndrome; Gorlin syndrome
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SUPT5H |
SPT5 homolog, DSIF elongation factor subunit |
- Formation of RNA Pol II elongation complex
- Formation of the Early Elongation Complex
- Formation of HIV elongation complex in the absence of HIV Tat
- Formation of the HIV-1 Early Elongation Complex
- RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
- Formation of HIV-1 elongation complex containing HIV-1 Tat
- Formation of HIV-1 elongation complex containing HIV-1 Tat
- Pausing and recovery of Tat-mediated HIV elongation
- Abortive elongation of HIV-1 transcript in the absence of Tat
- Tat-mediated HIV elongation arrest and recovery
- Tat-mediated elongation of the HIV-1 transcript
- HIV elongation arrest and recovery
- Pausing and recovery of HIV elongation
- RNA Polymerase II Pre-transcription Events
- TP53 Regulates Transcription of DNA Repair Genes
- RNA polymerase II transcribes snRNA genes
- mRNA Capping
- RNA Polymerase II Transcription Elongation
- RNA Pol II CTD phosphorylation and interaction with CE
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TBX3 |
T-box transcription factor 3 |
- Transcriptional and post-translational regulation of MITF-M expression and activity
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- Ulnar-mammary syndrome; Schinzel syndrome
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TBX6 |
T-box transcription factor 6 |
- Formation of paraxial mesoderm
- Somitogenesis
- Formation of the posterior neural plate
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TCEANC |
transcription elongation factor A N-terminal and central domain containing |
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TCF4 |
transcription factor 4 |
- Myogenesis
- Myogenesis
- TGFBR3 expression
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- Pitt-Hopkins syndrome, including: Pitt-Hopkins syndrome; Pitt-Hopkins-like syndrome
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TCF7L2 |
transcription factor 7 like 2 |
- Formation of the beta-catenin:TCF transactivating complex
- Formation of the beta-catenin:TCF transactivating complex
- Deactivation of the beta-catenin transactivating complex
- Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)
- Ca2+ pathway
- Binding of TCF/LEF:CTNNB1 to target gene promoters
- Repression of WNT target genes
- Repression of WNT target genes
- Signaling by TCF7L2 mutants
- Transcriptional Regulation by VENTX
- RUNX3 regulates WNT signaling
- Formation of definitive endoderm
- Regulation of MITF-M-dependent genes involved in cell cycle and proliferation
- Regulation of PD-L1(CD274) transcription
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- Type II diabetes mellitus
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TEAD4 |
TEA domain transcription factor 4 |
- YAP1- and WWTR1 (TAZ)-stimulated gene expression
- RUNX3 regulates YAP1-mediated transcription
- Formation of axial mesoderm
- Zygotic genome activation (ZGA)
- Regulation of PD-L1(CD274) transcription
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TENT5B |
terminal nucleotidyltransferase 5B |
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TFAP2D |
transcription factor AP-2 delta |
- Negative regulation of activity of TFAP2 (AP-2) family transcription factors
- Negative regulation of activity of TFAP2 (AP-2) family transcription factors
- Activation of the TFAP2 (AP-2) family of transcription factors
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THAP7 |
THAP domain containing 7 |
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TIGD3 |
tigger transposable element derived 3 |
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TMCC2 |
transmembrane and coiled-coil domain family 2 |
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TNS2 |
tensin 2 |
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TOX3 |
TOX high mobility group box family member 3 |
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TRAF1 |
TNF receptor associated factor 1 |
- Regulation of TNFR1 signaling
- TNFR1-induced NF-kappa-B signaling pathway
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TRAF2 |
TNF receptor associated factor 2 |
- Caspase activation via Death Receptors in the presence of ligand
- Regulation by c-FLIP
- RIPK1-mediated regulated necrosis
- CASP8 activity is inhibited
- TNFR1-induced proapoptotic signaling
- Regulation of TNFR1 signaling
- TNFR1-induced NF-kappa-B signaling pathway
- TNFR2 non-canonical NF-kB pathway
- Regulation of necroptotic cell death
- TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
- Ub-specific processing proteases
- Dimerization of procaspase-8
- TNF signaling
- TRAF6 mediated IRF7 activation
- TRAF6 mediated NF-kB activation
- TRAF6 mediated NF-kB activation
- Defective RIPK1-mediated regulated necrosis
- Regulation of NF-kappa B signaling
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TRIB3 |
tribbles pseudokinase 3 |
- PIP3 activates AKT signaling
- Activation of AKT2
- PPARA activates gene expression
- Negative regulation of the PI3K/AKT network
- CD28 dependent PI3K/Akt signaling
- VEGFR2 mediated vascular permeability
- Response of EIF2AK4 (GCN2) to amino acid deficiency
- Response of EIF2AK1 (HRI) to heme deficiency
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TRIM26 |
tripartite motif containing 26 |
- Interferon gamma signaling
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