FXR1 - New-wiki

Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
SPRY2	sprouty RTK signaling antagonist 2	Spry regulation of FGF signaling EGFR downregulation
SRPK2	SRSF protein kinase 2	Maturation of nucleoprotein	Adenine Purvalanol Phosphoaminophosphonic Acid-Adenylate Ester
SSNA1	SS nuclear autoantigen 1	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
STK16	serine/threonine kinase 16		Fostamatinib
STUB1	STIP1 homology and U-box containing protein 1	Downregulation of TGF-beta receptor signaling RIPK1-mediated regulated necrosis Regulation of TNFR1 signaling Regulation of necroptotic cell death Downregulation of ERBB2 signaling Regulation of RUNX2 expression and activity Regulation of PTEN stability and activity Antigen processing: Ubiquitination & Proteasome degradation
SUFU	SUFU negative regulator of hedgehog signaling	Degradation of GLI1 by the proteasome Degradation of GLI1 by the proteasome Degradation of GLI2 by the proteasome GLI3 is processed to GLI3R by the proteasome Hedgehog 'off' state Hedgehog 'on' state		Basal cell nevus syndrome; Nevoid basal cell carcinoma syndrome; Gorlin syndrome
SYT6	synaptotagmin 6
TACC2	transforming acidic coiled-coil containing protein 2
TASOR2	transcription activation suppressor family member 2
TBC1D22B	TBC1 domain family member 22B
TCEA2	transcription elongation factor A2
TDRD7	tudor domain containing 7
TLE5	TLE family member 5, transcriptional modulator	Repression of WNT target genes
TMPO	thymopoietin	RHOA GTPase cycle RHOC GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOD GTPase cycle RHOG GTPase cycle RHOJ GTPase cycle RAC3 GTPase cycle RHOF GTPase cycle
TNFAIP1	TNF alpha induced protein 1	RND3 GTPase cycle RND2 GTPase cycle
TRAF2	TNF receptor associated factor 2	Caspase activation via Death Receptors in the presence of ligand Regulation by c-FLIP RIPK1-mediated regulated necrosis CASP8 activity is inhibited TNFR1-induced proapoptotic signaling Regulation of TNFR1 signaling TNFR1-induced NF-kappa-B signaling pathway TNFR2 non-canonical NF-kB pathway Regulation of necroptotic cell death TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway Ub-specific processing proteases Dimerization of procaspase-8 TNF signaling TRAF6 mediated IRF7 activation TRAF6 mediated NF-kB activation TRAF6 mediated NF-kB activation Defective RIPK1-mediated regulated necrosis Regulation of NF-kappa B signaling
TRAP1	TNF receptor associated protein 1	Respiratory electron transport Citric acid cycle (TCA cycle)
TRIM3	tripartite motif containing 3	Interferon gamma signaling
TRIOBP	TRIO and F-actin binding protein
TRPM1	transient receptor potential cation channel subfamily M member 1	TRP channels Regulation of MITF-M-dependent genes involved in apoptosis		Congenital stationary night blindness (CSNB), including: CSNB type 1 (CSNB1); CSNB type 2 (CSNB2); CSNB autosomal dominant (CSNBAD); Oguchi disease/ CSNB Oguchi type (CSNBO)

Search Results for: FXR1