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IFT27
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intraflagellar transport 27 |
- Intraflagellar transport
- Intraflagellar transport
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IGFN1
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immunoglobulin like and fibronectin type III domain containing 1 |
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IHO1
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interactor of HORMAD1 1 |
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IKZF3
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IKAROS family zinc finger 3 |
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IL16
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interleukin 16 |
- Other interleukin signaling
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INPP5J
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inositol polyphosphate-5-phosphatase J |
- Synthesis of PIPs at the plasma membrane
- Synthesis of IP2, IP, and Ins in the cytosol
- Synthesis of IP3 and IP4 in the cytosol
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IQCE
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IQ motif containing E |
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IQUB
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IQ motif and ubiquitin domain containing |
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ISCU
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iron-sulfur cluster assembly enzyme |
- Maturation of replicase proteins
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ITGB5
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integrin subunit beta 5 |
- Cross-presentation of particulate exogenous antigens (phagosomes)
- Molecules associated with elastic fibres
- Integrin cell surface interactions
- Integrin cell surface interactions
- TGF-beta receptor signaling activates SMADs
- Syndecan interactions
- Syndecan interactions
- ECM proteoglycans
- Smooth Muscle Contraction
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ITPKB
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inositol-trisphosphate 3-kinase B |
- Synthesis of IP3 and IP4 in the cytosol
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ITSN2
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intersectin 2 |
- Cargo recognition for clathrin-mediated endocytosis
- Clathrin-mediated endocytosis
- RHOU GTPase cycle
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KANK2
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KN motif and ankyrin repeat domains 2 |
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KANSL1
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KAT8 regulatory NSL complex subunit 1 |
- HATs acetylate histones
- Formation of WDR5-containing histone-modifying complexes
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KAT5
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lysine acetyltransferase 5 |
- Formation of the beta-catenin:TCF transactivating complex
- Formation of the beta-catenin:TCF transactivating complex
- DNA Damage/Telomere Stress Induced Senescence
- HATs acetylate histones
- HDR through Single Strand Annealing (SSA)
- HDR through Homologous Recombination (HRR)
- Sensing of DNA Double Strand Breaks
- Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)
- Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
- Resolution of D-loop Structures through Holliday Junction Intermediates
- Nonhomologous End-Joining (NHEJ)
- Homologous DNA Pairing and Strand Exchange
- Processing of DNA double-strand break ends
- Presynaptic phase of homologous DNA pairing and strand exchange
- Regulation of TP53 Activity through Phosphorylation
- G2/M DNA damage checkpoint
- Estrogen-dependent gene expression
- Defective homologous recombination repair (HRR) due to BRCA1 loss of function
- Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function
- Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function
- Impaired BRCA2 binding to RAD51
- Impaired BRCA2 binding to PALB2
- Cardiogenesis
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- Coenzyme A
- S-Acetyl-Cysteine
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KDM1A
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lysine demethylase 1A |
- HDACs deacetylate histones
- HDMs demethylate histones
- Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
- Regulation of PTEN gene transcription
- Estrogen-dependent gene expression
- NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
- Potential therapeutics for SARS
- Negative Regulation of CDH1 Gene Transcription
- Factors involved in megakaryocyte development and platelet production
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KIAA1217
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KIAA1217 |
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KIFC3
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kinesin family member C3 |
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KRT1
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keratin 1 |
- Neutrophil degranulation
- Keratinization
- Formation of the cornified envelope
- Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
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- Ichthyosis hystrix, Curth-Macklin type
- Epidermolytic palmoplantar keratoderma (EPPK)
- Striate palmoplantar keratoderma
- Epidermolytic hyperkeratosis (EHK); Bullous congenital ichthyosiform erythroderma (BCIE)
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KRT18
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keratin 18 |
- Keratinization
- Formation of the cornified envelope
- Developmental Lineage of Mammary Gland Luminal Epithelial Cells
- Developmental Lineage of Mammary Gland Alveolar Cells
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