PYROXD1 and UPRT

Number of citations: 0 (PubMedID 16189514)
Data Source: HPRD (two hybrid)

		PYROXD1	UPRT
Name		pyridine nucleotide-disulphide oxidoreductase domain 1	uracil phosphoribosyltransferase homolog
Structure			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Sarcomere	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Protein Binding NAD(P)H Oxidase H2O2-forming Activity Oxidoreductase Activity	Nucleotide Binding Protein Binding GTP Binding Ribosylnicotinamide Kinase Activity Ribosylnicotinate Kinase Activity
	Biological Process	Cellular Response To Oxidative Stress	UMP Biosynthetic Process Female Pregnancy Lactation Response To Insulin
GWAS		No GWAS studies recorded	No GWAS studies recorded
Interacting Genes		3 interacting genes: APP CFTR UPRT	9 interacting genes: COMMD1 ERH GGA3 HSF2BP KAT5 NPM3 POLR2G PPL PYROXD1
Entrez ID		79912	139596
HPRD ID		07976	06640
Ensembl ID		ENSG00000121350	ENSG00000094841
Uniprot IDs		Q8WU10	A0A0A0MRR5 E9PSD7 Q96BW1
PDB IDs		6ZK7 8ORJ	Not available
GO Terms Enriched among Interactors		Acetylcholine Receptor Activator Activity Protein-folding Chaperone Binding Amyloid-beta Complex PTB Domain Binding Response To Purine-containing Compound Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Reproductive Process Regulation Of Response To Calcium Ion Developmental Maturation Early Endosome Membrane Recycling Endosome Amylin Binding Endosome To Plasma Membrane Transport Vesicle Cell Maturation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To CAMP Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To CAMP Positive Regulation Of Anion Channel Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Monoatomic Anion Transport Ribosylnicotinate Kinase Activity Ribosylnicotinamide Kinase Activity Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Positive Regulation Of Protein Transport Positive Regulation Of Enamel Mineralization Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Regulation Of Monoatomic Ion Transmembrane Transport Growth Factor Receptor Binding Main Axon Transepithelial Water Transport Regulation Of Body Fluid Levels Regulation Of Spontaneous Synaptic Transmission Positive Regulation Of Establishment Of Protein Localization	Positive Regulation Of Protein Metabolic Process Histone H2AK5 Acetyltransferase Activity Protein Targeting To Vacuole Nucleotide-excision Repair Establishment Of Protein Localization To Vacuole Protein Destabilization Protein Localization To Cell Surface Golgi To Plasma Membrane Transport Positive Regulation Of Cholesterol Import Nucleobase-containing Compound Metabolic Process Peptide Butyryltransferase Activity Peptide 2-hydroxyisobutyryltransferase Activity Peptide Crotonyltransferase Activity Protein Localization To Vacuole Negative Regulation Of Hypoxia-inducible Factor-1alpha Signaling Pathway DNA-templated Transcription Histone H2A Acetyltransferase Activity Peptide Lactyltransferase (CoA-dependent) Activity Post-Golgi Vesicle-mediated Transport Positive Regulation Of Endosome To Plasma Membrane Protein Transport Nucleic Acid Metabolic Process Piccolo Histone Acetyltransferase Complex DNA Repair Vesicle-mediated Transport To The Plasma Membrane Regulation Of Plasma Lipoprotein Particle Levels