HS3ST1

Name	heparan sulfate-glucosamine 3-sulfotransferase 1
Structure
Novel Interactors	1 novel interactors: PRKD1
Interactors	1 interactors: APP
GO Annotations	Cellular Component	Golgi Apparatus Golgi Lumen
	Molecular Function	Sulfotransferase Activity [heparan Sulfate]-glucosamine 3-sulfotransferase Activity Transferase Activity
	Biological Process	Glycosaminoglycan Biosynthetic Process Heparan Sulfate Proteoglycan Biosynthetic Process
Pathways	HS-GAG biosynthesis
Drugs	Adenosine 3',5'-diphosphate
GWAS	Alzheimer's disease ( 34099642 ) Alzheimer's disease (late onset) ( 24162737 30617256 ) Ankylosing spondylitis ( 30946743 ) Daytime sleep phenotypes ( 27126917 ) Exploratory eye movement dysfunction in schizophrenia (cognitive search score) ( 26242244 ) Intraocular pressure ( 30591961 ) Nonalcoholic fatty liver disease ( 22719876 ) Photic sneeze reflex ( 27182965 30899065 ) Response to ziprazidone in schizophrenia ( 29503163 ) Rheumatoid arthritis ( 30891314 )
Entrez ID	9957
HPRD ID	04455
Ensembl ID	ENSG00000002587
Uniprot IDs	O14792
PDB IDs	1ZRH
GO Terms Enriched among Interactors ?	Response To Norepinephrine Cellular Response To Norepinephrine Stimulus Cellular Response To Catecholamine Stimulus Response To Catecholamine Defense Response To Gram-negative Bacterium Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Calcium Ion Transmembrane Transport Regulation Of Response To Calcium Ion Calcium-mediated Signaling Positive Regulation Of Chemotaxis Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Supramolecular Fiber Organization Regulation Of Protein Localization To Nucleus Regulation Of Skeletal Muscle Contraction By Modulation Of Calcium Ion Sensitivity Of Myofibril Regulation Of Chemotaxis Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Positive Regulation Of Establishment Of Protein Localization Response To Growth Factor Endosome To Plasma Membrane Transport Vesicle Cellular Response To Growth Factor Stimulus Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Monoatomic Ion Transmembrane Transport Defense Response To Bacterium Regulation Of Calcium Ion Transport Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Regulation Of Monoatomic Cation Transmembrane Transport Regulation Of Endocytosis Positive Regulation Of Protein Transport Regulation Of Metal Ion Transport Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Monoatomic Ion Transport Axon Midline Choice Point Recognition Regulation Of Supramolecular Fiber Organization Positive Regulation Of Amyloid Fibril Formation Response To Bacterium Growth Factor Receptor Binding Main Axon