CACNA1G

Name	calcium voltage-gated channel subunit alpha1 G
Structure
Novel Interactors	1 novel interactors: MKS1
Interactors	2 interactors: RANBP9 UBQLN4
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Voltage-gated Calcium Channel Complex Membrane Monoatomic Ion Channel Complex Synapse
	Molecular Function	Monoatomic Ion Channel Activity Voltage-gated Calcium Channel Activity Calcium Channel Activity High Voltage-gated Calcium Channel Activity Low Voltage-gated Calcium Channel Activity Voltage-gated Calcium Channel Activity Involved In AV Node Cell Action Potential Voltage-gated Calcium Channel Activity Involved SA Node Cell Action Potential Scaffold Protein Binding
	Biological Process	Action Potential Regulation Of Heart Rate Sinoatrial Node Development Monoatomic Ion Transport Calcium Ion Transport Chemical Synaptic Transmission Response To Nickel Cation Monoatomic Ion Transmembrane Transport Regulation Of Membrane Potential Transmembrane Transport Regulation Of Atrial Cardiac Muscle Cell Membrane Depolarization Regulation Of Biological Quality Calcium Ion Import Calcium Ion Transmembrane Transport Cardiac Muscle Cell Action Potential Involved In Contraction SA Node Cell Action Potential AV Node Cell Action Potential SA Node Cell To Atrial Cardiac Muscle Cell Signaling AV Node Cell To Bundle Of His Cell Signaling Membrane Depolarization During AV Node Cell Action Potential Membrane Depolarization During SA Node Cell Action Potential Regulation Of Heart Rate By Cardiac Conduction Calcium Ion Import Across Plasma Membrane
Pathways	NCAM1 interactions Smooth Muscle Contraction
Drugs	Ergocalciferol Enflurane Trimethadione Spironolactone Cinnarizine Ethosuximide Nicardipine Nicardipine Verapamil Verapamil Zonisamide Nifedipine Mibefradil Flunarizine Methsuximide Nilvadipine Cannabidiol Trimebutine Barnidipine Benidipine Efonidipine Efonidipine Efonidipine Manidipine Manidipine Butamben Bioallethrin Bioallethrin Medical Cannabis Nabiximols
GWAS	Adventurousness ( 30643258 ) Alzheimer's disease (cognitive decline) ( 23535033 ) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098 ) PR interval ( 32439900 ) Total cholesterol levels ( 30498476 )
Entrez ID	8913
HPRD ID	04961
Ensembl ID	ENSG00000006283
Uniprot IDs	O43497
PDB IDs	6KZO 6KZP
GO Terms Enriched among Interactors ?	Common Bile Duct Development Cell Surface Receptor Signaling Pathway Involved In Heart Development Smoothened Signaling Pathway Involved In Regulation Of Secondary Heart Field Cardioblast Proliferation Negative Regulation Of Autophagosome Maturation Nuclear Proteasome Complex Cytosolic Proteasome Complex K48-linked Polyubiquitin Modification-dependent Protein Binding