DISP1

Name	dispatched RND transporter family member 1
Structure
Novel Interactors	1 novel interactors: MTARC1
Interactors	1 interactors: LAPTM5
GO Annotations	Cellular Component	Membrane
	Molecular Function	Protein Binding Molecular Carrier Activity
	Biological Process	Smoothened Signaling Pathway Patched Ligand Maturation Determination Of Left/right Symmetry Embryonic Pattern Specification Dorsal/ventral Pattern Formation Peptide Transport Diaphragm Development
GWAS	Heel bone mineral density ( 30598549 ) Response to antiepileptic mood-stabilizing treatment in bipolar disorder ( 32627186 )
Entrez ID	84976
HPRD ID	06326
Ensembl ID	ENSG00000154309
Uniprot IDs	Q96F81
PDB IDs	6XE6 7E2G 7E2H 7E2I
GO Terms Enriched among Interactors ?	Induction Of Programmed Cell Death Negative Regulation Of Pre-B Cell Receptor Expression Negative Regulation Of Autophagic Cell Death Positive Regulation Of Lysosomal Membrane Permeability Regulation Of Lysosomal Membrane Permeability Nitric-oxide Synthase Complex Nitrate Reductase Activity Oxidoreductase Activity, Acting On Other Nitrogenous Compounds As Donors Detoxification Of Nitrogen Compound Cellular Detoxification Of Nitrogen Compound Nitrate Metabolic Process Molybdenum Ion Binding Nitrite Reductase Activity Molybdopterin Cofactor Binding Nitrite Reductase (NO-forming) Activity Positive Regulation Of Receptor Catabolic Process Defense Response To Tumor Cell Golgi To Lysosome Transport Negative Regulation Of Activated T Cell Proliferation Lysosomal Membrane Organization Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Golgi To Vacuole Transport Nitric Oxide Biosynthetic Process Positive Regulation Of Macrophage Cytokine Production Negative Regulation Of Interleukin-2 Production Protein Targeting To Lysosome Negative Regulation Of T Cell Receptor Signaling Pathway Nitric Oxide Metabolic Process Positive Regulation Of Membrane Permeability Reactive Nitrogen Species Metabolic Process Negative Regulation Of B Cell Activation Positive Regulation Of Myeloid Leukocyte Cytokine Production Involved In Immune Response Regulation Of Activated T Cell Proliferation Regulation Of Macrophage Cytokine Production Positive Regulation Of Interleukin-12 Production Negative Regulation Of Type II Interferon Production Protein Sequestering Activity Protein Targeting To Vacuole Regulation Of T Cell Receptor Signaling Pathway Pyridoxal Phosphate Binding Protein Localization To Lysosome Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Establishment Of Protein Localization To Vacuole Regulation Of Interleukin-2 Production Positive Regulation Of Cytokine-mediated Signaling Pathway Regulation Of Interleukin-12 Production Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Response To Cytokine Stimulus Regulation Of Membrane Permeability Negative Regulation Of T Cell Proliferation