FBXO30

Name	F-box protein 30
Structure
Interactors	6 interactors: ACVR1 APC SMAD1 SMAD4 SMURF1 UBC
GO Annotations	Cellular Component	Cytosol
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Chromatin Organization Chromosome Segregation Gene Expression Protein Ubiquitination Chromosome Condensation
Pathways	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
GWAS	No GWAS studies recorded
Entrez ID	84085
HPRD ID	10953
Ensembl ID	ENSG00000118496
Uniprot IDs	Q8TB52
PDB IDs	2YRE
GO Terms Enriched among Interactors ?	BMP Signaling Pathway I-SMAD Binding Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Enzyme-linked Receptor Protein Signaling Pathway SMAD Binding SMAD Protein Complex Heteromeric SMAD Protein Complex Pattern Specification Process Transforming Growth Factor Beta Receptor Signaling Pathway Osteoblast Differentiation Negative Regulation Of Activin Receptor Signaling Pathway Cardiac Conduction System Development Gastrulation With Mouth Forming Second Cell Fate Commitment SMAD Protein Signal Transduction Outflow Tract Septum Morphogenesis Endothelial Cell Differentiation Tissue Development Activin Receptor Signaling Pathway Cellular Response To BMP Stimulus Positive Regulation Of Multicellular Organismal Process Regulation Of Activin Receptor Signaling Pathway R-SMAD Binding Ventricular Septum Morphogenesis Cellular Response To Growth Factor Stimulus Positive Regulation Of SMAD Protein Signal Transduction Positive Regulation Of Cell Differentiation Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Ubiquitin Protein Ligase Binding Gastrulation Cell Surface Receptor Signaling Pathway Response To Growth Factor Mesoderm Development Positive Regulation Of MiRNA Transcription Positive Regulation Of Cell Projection Organization Embryonic Pattern Specification Positive Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Cardiac Muscle Tissue Development Positive Regulation Of MiRNA Metabolic Process Negative Regulation Of Cell Cycle G1/S Phase Transition Intracellular Iron Ion Homeostasis Regulation Of SMAD Protein Signal Transduction Tissue Morphogenesis Positive Regulation Of Cellular Component Organization Negative Regulation Of Muscle Cell Differentiation Cardiac Septum Morphogenesis Positive Regulation Of Osteoblast Differentiation Regulation Of MiRNA Transcription