PRR5L

Name	proline rich 5 like
Structure	No pdb structure
Interactors	15 interactors: CCDC91 EFHC1 FHL2 FHL3 HSF2BP KANK2 MAD2L2 MISP MLH1 MORN3 MTOR PHAF1 SCNM1 USP2 ZMYND12
GO Annotations	Cellular Component	TORC2 Complex
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding
	Biological Process	Negative Regulation Of Protein Phosphorylation Negative Regulation Of Signal Transduction Regulation Of Fibroblast Migration Cellular Response To Oxidative Stress TORC2 Signaling Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of MRNA Catabolic Process Positive Regulation Of Intracellular Protein Transport
GWAS	A body shape index ( 34021172 ) Allergic disease (asthma, hay fever or eczema) ( 29679657 ) Asthma ( 32296059 31619474 31361310 30929738 ) Asthma (childhood onset) ( 30929738 ) Atopic dermatitis ( 23727859 26482879 ) Hip index ( 34021172 ) Idiopathic inflammatory myopathy ( 26362759 ) Inflammatory skin disease ( 25574825 ) Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761 ) Mean corpuscular volume ( 32888494 ) Multiple sclerosis ( 31604244 24076602 ) Photic sneeze reflex ( 27182965 ) Red blood cell count ( 32888494 ) Waist circumference adjusted for body mass index ( 34021172 ) Waist-hip index ( 34021172 ) Waist-to-hip ratio adjusted for BMI ( 34021172 )
Entrez ID	79899
HPRD ID	07854
Ensembl ID	ENSG00000135362
Uniprot IDs	B3KNU3 Q6MZQ0
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Negative Regulation Of Calcineurin-NFAT Signaling Cascade Negative Regulation Of Calcium-mediated Signaling Regulation Of Signal Transduction By P53 Class Mediator Cardiac Cell Development Regulation Of Calcineurin-mediated Signaling Regulation Of Calcineurin-NFAT Signaling Cascade Cardiac Muscle Cell Development Organelle Organization Positive Regulation Of SCF-dependent Proteasomal Ubiquitin-dependent Catabolic Process Regulation Of Isotype Switching Positive Regulation Of Immunoglobulin Mediated Immune Response Double-strand Break Repair Male Meiotic Nuclear Division Negative Regulation Of DNA Recombination Positive Regulation Of Isotype Switching Somatic Diversification Of Immunoglobulins Involved In Immune Response Late Recombination Nodule Somatic Diversification Of Immunoglobulins Meiotic Metaphase I Homologous Chromosome Alignment DNA Damage Response, Signal Transduction Resulting In Transcription Cytoskeleton Organization Positive Regulation Of Immunoglobulin Production Atrial Cardiac Muscle Cell Development Regulation Of Locomotor Rhythm TFIIIC-class Transcription Factor Complex Binding Meiotic Spindle Midzone Assembly Meiosis I Cell Cycle Process Meiotic Metaphase Chromosome Alignment Chiasma Negative Regulation Of Vitamin D Receptor Signaling Pathway Striated Muscle Cell Development Meiotic Nuclear Division Positive Regulation Of DNA Recombination