SURF6

Name	surfeit 6
Structure
Interactors	6 interactors: ADARB1 CSNK2A1 FAM9B RBFOX2 RBM4 RPL22
GO Annotations	Cellular Component	Granular Component Nucleus Nucleoplasm Chromosome Nucleolus
	Molecular Function	DNA Binding RNA Binding Protein Binding Molecular Condensate Scaffold Activity
	Biological Process	Ribosome Biogenesis Ribosomal Large Subunit Biogenesis Ribosomal Small Subunit Biogenesis
GWAS	Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359 ) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359 ) Apolipoprotein A1 levels ( 32203549 ) Apolipoprotein B levels ( 32203549 ) Blood protein levels in cardiovascular risk ( 28369058 ) Coagulation factor levels ( 23267103 ) Epithelial ovarian cancer ( 25134534 ) HDL cholesterol levels ( 32203549 ) LDL cholesterol levels ( 30698716 32203549 ) LDL cholesterol levels in current drinkers ( 30698716 ) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716 ) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716 ) Malaria ( 31844061 ) Serum alkaline phosphatase levels ( 24094242 ) Tonsillectomy ( 28928442 27182965 ) Triglyceride levels ( 32203549 ) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716 ) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716 )
Entrez ID	6838
HPRD ID	01714
Ensembl ID	ENSG00000148296
Uniprot IDs	O75683
PDB IDs	8FKP 8FKQ 8FKR 8FKS
GO Terms Enriched among Interactors ?	MRNA Metabolic Process MRNA Binding Hypoglossal Nerve Morphogenesis MRNA Processing Negative Regulation Of Translational Initiation Cap-independent Translational Initiation Regulation Of Alternative MRNA Splicing, Via Spliceosome IRES-dependent Translational Initiation Of Linear MRNA Translation At Presynapse RNA Metabolic Process Regulation Of Translational Initiation Pre-mRNA Intronic Pyrimidine-rich Binding Circadian Regulation Of Translation Regulation Of MRNA Splicing, Via Spliceosome RNA Binding Negative Regulation Of Protein Metabolic Process Spinal Cord Ventral Commissure Morphogenesis Facial Nerve Morphogenesis Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Regulation Of MRNA Processing Negative Regulation Of Protein Kinase Activity By Regulation Of Protein Phosphorylation Double-stranded RNA Adenosine Deaminase Activity Adenosine To Inosine Editing Negative Regulation Of Translation Positive Regulation Of Aggrephagy Regulation Of RNA Splicing TRNA-specific Adenosine Deaminase Activity RNA Processing Adenosine Deaminase Activity Nucleic Acid Metabolic Process Nucleus Deaminase Activity Nucleoplasm Rhythmic Process Negative Regulation Of Translation In Response To Stress Double-strand Break Repair Via Classical Nonhomologous End Joining Insulin Secretion Involved In Cellular Response To Glucose Stimulus Pre-mRNA Intronic Binding Neuromuscular Process Controlling Posture Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Cranial Nerve Morphogenesis Aggrephagy Protein Targeting To Vacuole Involved In Autophagy Motor Neuron Apoptotic Process Regulation Of MRNA Metabolic Process Enteroendocrine Cell Differentiation Nucleobase-containing Compound Metabolic Process Base Conversion Or Substitution Editing Negative Regulation Of Macromolecule Metabolic Process