DLK2

Name	delta like non-canonical Notch ligand 2
Structure	No pdb structure
Interactors	4 interactors: ADAMTSL4 APP KRTAP4-12 PLSCR1
GO Annotations	Cellular Component	Membrane
	Molecular Function	Notch Binding Calcium Ion Binding Identical Protein Binding
	Biological Process	Regulation Of Fat Cell Differentiation Negative Regulation Of Notch Signaling Pathway
GWAS	Blood protein levels ( 30072576 ) Waist-to-hip ratio adjusted for BMI ( 26426971 ) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971 ) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971 ) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971 )
Entrez ID	65989
HPRD ID	16855
Ensembl ID	ENSG00000171462
Uniprot IDs	Q5T3T9 Q6UY11
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Response To Lead Ion Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Apoptotic Process Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Programmed Cell Death Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Cell Death Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Phosphatidylserine Biosynthetic Process Mercury Ion Binding Lead Ion Binding Phosphatidylserine Exposure On Apoptotic Cell Surface Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Pigment Cell Development Membrane Raft Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Extracellular Matrix Organization Extracellular Structure Organization Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Interstitial Matrix Endoplasmic Reticulum Lumen Heparan Sulfate Binding Signaling Receptor Activator Activity Regulation Of Endocytosis