TGIF2

Name	TGFB induced factor homeobox 2
Structure	No pdb structure
Novel Interactors	1 novel interactors: PLS3
Interactors	5 interactors: FBXO7 HDAC1 RBBP8 SMAD3 TARBP2
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Centrosome
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of Gastrulation Neuron Differentiation Amacrine Cell Differentiation Nodal Signaling Pathway Retina Development In Camera-type Eye Positive Regulation Of Amacrine Cell Differentiation
Pathways	Downregulation of SMAD2/3:SMAD4 transcriptional activity SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Negative Regulation of CDH1 Gene Transcription
GWAS	No GWAS studies recorded
Entrez ID	60436
HPRD ID	06293
Ensembl ID	ENSG00000118707
Uniprot IDs	Q9GZN2
PDB IDs	Not available
GO Terms Enriched among Interactors ?	RNA Polymerase II-specific DNA-binding Transcription Factor Binding Endoderm Development MiRNA Processing Enzyme Binding Transcription Repressor Complex Promoter-specific Chromatin Binding Transcription Corepressor Binding Negative Regulation Of Lung Blood Pressure Nuclear Mineralocorticoid Receptor Binding Structural Constituent Of Presynaptic Actin Cytoskeleton Regulation Of SiRNA Processing Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Ubiquitin Binding Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Krueppel-associated Box Domain Binding Positive Regulation Of Transforming Growth Factor Beta3 Production Regulation Of Muscle Cell Differentiation Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Protein Decrotonylase Activity Negative Regulation Of Cell Differentiation Histone Decrotonylase Activity Protein Lysine Delactylase Activity Fungiform Papilla Formation Regulation Of Cell Differentiation Sterol Response Element Binding Regulation Of Lung Blood Pressure Paraxial Mesoderm Morphogenesis Negative Regulation Of Mitotic Cell Cycle Phase Transition Global Gene Silencing By MRNA Cleavage Negative Regulation Of Defense Response To Virus By Host Lewy Body Core Negative Regulation Of Intracellular Signal Transduction DNA-binding Transcription Factor Binding Hair Follicle Placode Formation Regulation Of Intrinsic Apoptotic Signaling Pathway Mesoderm Morphogenesis Immune System Development Transcription Corepressor Activity Regulation Of Intracellular Signal Transduction Negative Regulation Of Apoptotic Process Positive Regulation Of Cell Differentiation Transdifferentiation SMAD Protein Complex Pericardium Development Trophoblast Cell Migration Presynaptic Cytoskeleton Organization Presynaptic Actin Cytoskeleton Organization