STAB2

Name	stabilin 2
Structure
Interactors	1 interactors: ITGB5
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane External Side Of Plasma Membrane Membrane Endocytic Vesicle Membrane
	Molecular Function	Low-density Lipoprotein Particle Receptor Activity Scavenger Receptor Activity Calcium Ion Binding Protein Binding Hyaluronic Acid Binding Protein-disulfide Reductase Activity Low-density Lipoprotein Particle Binding Cargo Receptor Activity
	Biological Process	Angiogenesis Endocytosis Receptor-mediated Endocytosis Cell Adhesion Hyaluronan Catabolic Process Defense Response To Bacterium Defense Response To Gram-positive Bacterium
Pathways	Hyaluronan metabolism Hyaluronan degradation Scavenging by Class H Receptors
Drugs	Hyaluronic acid
GWAS	A body shape index ( 34021172 ) Adverse response to drug ( 30420678 ) Coronary restenosis ( 21878436 ) Daytime sleep phenotypes ( 27126917 ) Factor VIII levels ( 30586737 ) Low vWF levels ( 26486471 ) Monocyte count ( 32888494 ) Response to methotrexate in juvenile idiopathic arthritis ( 24709693 ) Sense of smell ( 26632684 ) Stem cell growth factor beta levels ( 27989323 ) Systemic lupus erythematosus ( 33493351 ) vWF and FVIII levels ( 21810271 ) vWF levels ( 20231535 30586737 )
Entrez ID	55576
HPRD ID	10542
Ensembl ID	ENSG00000136011
Uniprot IDs	Q8WWQ8
PDB IDs	5N86
GO Terms Enriched among Interactors ?	Integrin Alphav-beta5 Complex Wound Healing, Spreading Of Epidermal Cells Wound Healing, Spreading Of Cells Epithelial Cell-cell Adhesion Stress Fiber Assembly Cell Adhesion Mediated By Integrin Integrin Complex Contractile Actin Filament Bundle Assembly Endodermal Cell Differentiation Formation Of Primary Germ Layer Actin Filament Bundle Assembly Actin Filament Bundle Organization Phagocytic Vesicle Virus Receptor Activity Symbiont Entry Into Host Cell Integrin-mediated Signaling Pathway Transforming Growth Factor Beta Receptor Signaling Pathway Cell-matrix Adhesion Actomyosin Structure Organization Cell-substrate Adhesion Integrin Binding Biological Process Involved In Interaction With Host Receptor Complex Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Actin Filament Organization Actin Cytoskeleton Organization Signaling Receptor Binding Actin Filament-based Process Focal Adhesion