STK26

Name	serine/threonine kinase 26
Structure
Interactors	13 interactors: APP CEP76 CFTR GOLGA2 GRB14 IKZF3 MBP NEDD4 OGT RAF1 SRPK1 TRAF6 TRIM27
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Golgi-associated Vesicle Cytosol Vesicle Membrane Membrane Apical Plasma Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome Cell Periphery FAR/SIN/STRIPAK Complex
	Molecular Function	Nucleotide Binding Magnesium Ion Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Identical Protein Binding Protein Homodimerization Activity Metal Ion Binding Protein Serine Kinase Activity
	Biological Process	Protein Phosphorylation Apoptotic Process Cellular Response To Starvation Negative Regulation Of Cell Migration Cellular Response To Oxidative Stress Intracellular Signal Transduction Regulation Of Apoptotic Process Protein Autophosphorylation Positive Regulation Of Microvillus Assembly
Pathways	Apoptotic cleavage of cellular proteins
Drugs	2-[4-[4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]quinazolin-2-yl]iminocyclohexa-2,5-dien-1-yl]acetonitrile Fostamatinib
GWAS	Gestational age at birth (maternal effect) ( 28877031 )
Entrez ID	51765
HPRD ID	06663
Ensembl ID	ENSG00000134602
Uniprot IDs	Q9P289
PDB IDs	3GGF 3W8I 4FZA 4FZD 4FZF 4GEH 5XY9 5YF4 7B36
GO Terms Enriched among Interactors ?	Positive Regulation Of Protein Metabolic Process Protein-containing Complex Enzyme Binding Cytosol Protein K63-linked Ubiquitination Positive Regulation Of Macromolecule Metabolic Process Innate Immune Response Positive Regulation Of Interleukin-6 Production Regulation Of Protein Metabolic Process Response To Other Organism Protein Modification Process Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Immune Response Positive Regulation Of Metabolic Process Intracellular Signal Transduction Homeostatic Process Defense Response To Symbiont Defense Response To Other Organism Regulation Of Interleukin-6 Production Positive Regulation Of Biosynthetic Process Response To External Biotic Stimulus Cytoplasm Immune System Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Receptor Localization To Synapse Regulation Of Protein Localization To Synapse Defense Response Negative Regulation Of Signal Transduction Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Proteolysis Amyloid-beta Complex Regulation Of Phosphorus Metabolic Process Growth Cone Lamellipodium Regulation Of Primary Metabolic Process Protein Metabolic Process Positive Regulation Of Cytokine Production Regulation Of Response To Calcium Ion Regulation Of Glycolytic Process Negative Regulation Of Transcription By RNA Polymerase II Response To Stress Amylin Binding Negative Regulation Of Signaling Positive Regulation Of Toll Signaling Pathway Developmental Process Intracellular Chemical Homeostasis Leukocyte Activation Negative Regulation Of Cell Communication Establishment Of Localization In Cell Regulation Of Cellular Localization Intracellularly ATP-gated Chloride Channel Activity