CLEC1B

Name	C-type lectin domain family 1 member B
Structure
Interactors	2 interactors: NINL RACK1
GO Annotations	Cellular Component	Plasma Membrane Cell Surface Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding Carbohydrate Binding
	Biological Process	Defense Response Signal Transduction Cell Surface Receptor Signaling Pathway Platelet Formation
Pathways	GPVI-mediated activation cascade Heme signaling
GWAS	Blood protein levels ( 30072576 ) Malaria ( 31844061 )
Entrez ID	51266
HPRD ID	09490
Ensembl ID	ENSG00000165682
Uniprot IDs	Q9P126
PDB IDs	2C6U 3WSR 3WWK
GO Terms Enriched among Interactors ?	IRE1-RACK1-PP2A Complex Negative Regulation Of Translational Frameshifting Negative Regulation Of Translational Elongation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To Hydrogen Peroxide Positive Regulation Of Membrane Depolarization Positive Regulation Of Gastrulation Cysteine-type Endopeptidase Activator Activity Involved In Apoptotic Process Positive Regulation Of Golgi To Plasma Membrane Protein Transport Regulation Of Translational Elongation Negative Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Positive Regulation Of Mitochondrial Depolarization Ion Channel Inhibitor Activity Regulation Of Golgi To Plasma Membrane Protein Transport BH3 Domain Binding Protein Tyrosine Kinase Inhibitor Activity Microtubule Anchoring At Centrosome Microtubule Anchoring At Microtubule Organizing Center Regulation Of Gastrulation Positive Regulation Of Embryonic Development Translation Regulator Activity Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Phagocytosis Regulation Of Establishment Of Cell Polarity Regulation Of Mitochondrial Depolarization Regulation Of Establishment Or Maintenance Of Cell Polarity Negative Regulation Of Endoplasmic Reticulum Unfolded Protein Response Protein Serine/threonine Kinase Inhibitor Activity Small Ribosomal Subunit Microtubule Anchoring Phagocytic Cup Negative Regulation Of Protein Binding Cyclin Binding Regulation Of Endoplasmic Reticulum Unfolded Protein Response Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Rescue Of Stalled Ribosome Negative Regulation Of Smoothened Signaling Pathway Cytosolic Small Ribosomal Subunit SH2 Domain Binding Gastrulation Regulation Of Protein Binding Regulation Of Membrane Depolarization Protein Kinase C Binding Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Pigmentation Ribosome Disassembly Negative Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Cellular Response To Glucose Stimulus Translational Elongation Negative Regulation Of Endocytosis