NFX1

Name	nuclear transcription factor, X-box binding 1
Structure	No pdb structure
Novel Interactors	3 novel interactors: CDKN2A PPP1R16B SIGMAR1
Interactors	5 interactors: ELAVL4 MAML3 UBC UBE2N UBE3A
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Nucleolus Cytosol Plasma Membrane
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Nucleic Acid Binding DNA Binding DNA-binding Transcription Factor Activity RNA Binding Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Inflammatory Response Protein Ubiquitination Negative Regulation Of MHC Class II Biosynthetic Process Protein Autoubiquitination
GWAS	Fasting glucose ( 34059833 )
Entrez ID	4799
HPRD ID	11936
Ensembl ID	ENSG00000086102
Uniprot IDs	Q12986
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Positive Regulation Of Post-translational Protein Modification Protein Modification By Small Protein Conjugation Protein Ubiquitination Regulation Of Protein Ubiquitination Regulation Of Post-translational Protein Modification Protein Polyubiquitination Post-translational Protein Modification Ligase Inhibitor Activity Negative Regulation Of TORC1 Signaling Sperm Entry Positive Regulation Of Golgi Lumen Acidification Protein K63-linked Ubiquitination Positive Regulation Of Protein Modification Process Negative Regulation Of TOR Signaling Pre-mRNA Intronic Pyrimidine-rich Binding Regulation Of TORC1 Signaling Positive Regulation Of Protein Ubiquitination Positive Regulation Of Macrophage Apoptotic Process Apoptotic Process Involved In Mammary Gland Involution UBC13-MMS2 Complex Regulation Of Golgi Lumen Acidification Positive Regulation Of Apoptotic Process Involved In Mammary Gland Involution Senescence-associated Heterochromatin Focus Growth Cone Modification-dependent Protein Catabolic Process Ubiquitin Conjugating Enzyme Complex Negative Regulation Of Protein Neddylation Ubiquitin-protein Transferase Inhibitor Activity Negative Regulation Of Mammary Gland Epithelial Cell Proliferation Negative Regulation Of Immature T Cell Proliferation In Thymus Regulation Of TOR Signaling Positive Regulation Of Cellular PH Reduction Mitochondrial Depolarization Oncogene-induced Cell Senescence Negative Regulation Of Immature T Cell Proliferation Positive Regulation Of Apoptotic Process Involved In Morphogenesis Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Modification Process RNA Binding Positive Regulation Of 3'-UTR-mediated MRNA Stabilization Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Protein Localization To Lysosome G Protein-coupled Opioid Receptor Activity Myosin Phosphatase Regulator Activity Positive Regulation Of Transcription Of Notch Receptor Target Positive Regulation Of Apoptotic Process Involved In Development Positive Regulation Of Protein K63-linked Ubiquitination Protein Modification Process Negative Regulation Of Ubiquitin Protein Ligase Activity Positive Regulation Of Myeloid Cell Apoptotic Process